Evidence map›Paper›PMID 32021330›Full record

ArticleInfection and drug resistance2020

Transcriptome Analysis Reveals the Resistance Mechanism of

Jun Hong, Honghao Jiang, Jianye Hu, Lianzhe Wang, Ruifang Liu

Open access · goldAbstract read
In one paragraph

Article in Infection and drug resistance, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Jun HongCollege of Life Science and Engineering, Henan University of Urban Construction, Ping Dingshan 467036, People's Republic of China.
Honghao JiangCollege of Life Science and Engineering, Henan University of Urban Construction, Ping Dingshan 467036, People's Republic of China.
Jianye HuCollege of Life Science and Engineering, Henan University of Urban Construction, Ping Dingshan 467036, People's Republic of China.
Lianzhe WangCollege of Life Science and Engineering, Henan University of Urban Construction, Ping Dingshan 467036, People's Republic of China.
Ruifang LiuCollege of Life Science and Engineering, Henan University of Urban Construction, Ping Dingshan 467036, People's Republic of China.
Henan University of Urban Construction · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTachyplesin I is a cationic antimicrobial peptide with a typical cyclic antiparallel β-sheet structure. We previously demonstrated that long-term continuous exposure to increased concentration of tachyplesin I can induce resistant Gram-negative bacteria. However, no significant information is available about the resistance mechanism of MATERIALS AND

methodsIn this study, the global gene expression profiling of

resultsTranscriptome sequencing detected 672 upregulated and 787 downregulated genes, covering Clusters of Orthologous Groups (COGs) of

conclusionOur results indicated that

Indexed as

antibiotic resistancedifferentially expressed genesouter membrane permeabilityouter membrane proteinsP. aeruginosatachyplesin I

Identifiers

PMID32021330
PMCPMC6970625
OpenAlexW2998739198

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.