Evidence map›Paper›PMID 32021329›Full record

ArticleInfection and drug resistance2020

Characterization of blaNDM-1- and blaSHV-12-Positive IncX3 Plasmid in an

Peihan Li, Yanfeng Lin, Xiaofeng Hu, Yuqi Liu, Mei Xue, Lang Yang, Jinhui Li, Lei Zha, Kaiying Wang, Kezong Qi and 3 more

Open access · goldAbstract read
In one paragraph

Article in Infection and drug resistance, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.5field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Evolution, dissemination, and genetic dynamics of the carbapenem resistance geneFrontiers in cellular and infection microbiology · 2025
    Article
  3. Article
  4. AreFoods (Basel, Switzerland) · 2022
    Article
  5. Molecular characterization of NDM-1-producing carbapenem-resistantFrontiers in cellular and infection microbiology · 2022
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Peihan Li *Academy of Military Medical Sciences, Academy of Military Sciences, Beijing, People's Republic of China.
Yanfeng Lin *Academy of Military Medical Sciences, Academy of Military Sciences, Beijing, People's Republic of China.
Xiaofeng Hu *Center for Disease Control and Prevention of PLA, Beijing, People's Republic of China.
Yuqi LiuAcademy of Military Medical Sciences, Academy of Military Sciences, Beijing, People's Republic of China.
Mei XueAnhui Province Key Laboratory of Veterinary Pathobiology and Disease Control, Anhui Agricultural University, Anhui, People's Republic of China.ORCID 0000-0002-2901-2801
Lang YangAcademy of Military Medical Sciences, Academy of Military Sciences, Beijing, People's Republic of China.
Jinhui LiCenter for Disease Control and Prevention of PLA, Beijing, People's Republic of China.
Lei ZhaCenter for Disease Control and Prevention of PLA, Beijing, People's Republic of China.
Kaiying WangAcademy of Military Medical Sciences, Academy of Military Sciences, Beijing, People's Republic of China.
Kezong QiAnhui Province Key Laboratory of Veterinary Pathobiology and Disease Control, Anhui Agricultural University, Anhui, People's Republic of China.
Shaofu QiuCenter for Disease Control and Prevention of PLA, Beijing, People's Republic of China.
Peng LiCenter for Disease Control and Prevention of PLA, Beijing, People's Republic of China.
Hongbin SongCenter for Disease Control and Prevention of PLA, Beijing, People's Republic of China.
Academy of Military Medical Sciences · CNBeijing Center for Disease Prevention and Control · CNAnhui Agricultural University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeCarbapenem-resistant MATERIALS AND

methodsEcHK001 was recovered from the sputum sample of a patient. Species identification and antimicrobial susceptibility testing were performed using the VITEK 2 system, while further classification was carried out by hsp60 typing. The presence of NDM-1 was detected by PCR and sequencing. Conjugation experiments and southern blotting were carried out to determine the transferability of the NDM-1-carrying plasmid. Whole-genome sequencing and analysis were conducted to better understand the molecular characteristics of the multi-drug resistant isolate.

resultsStrain EcHK001 was classified as

conclusionThe rapid spread of the recurrent IncX3 plasmid highlights the need for continuous surveillance of the NDM-1 dissemination. The presence of mutations in existing carbapenem-resistant genes may generate potential new variants and raise serious challenges for clinical treatment.

Indexed as

enterobacter hormaecheimultidrug-resistantNDM-1SHV-12

Identifiers

PMID32021329
PMCPMC6968821
OpenAlexW3000248265

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.