Evidence map›Paper›PMID 32021218›Full record

ReviewNeuropsychiatric disease and treatment2020

Effects of Remote Ischemic Conditioning on Cerebral Hemodynamics in Ischemic Stroke.

Chen Qin, Xiuli Yan, Hang Jin, Ruyi Zhang, Yaode He, Xin Sun, Yihe Zhang, Zhen-Ni Guo, Yi Yang

Open access · goldAbstract readReview
In one paragraph

Review in Neuropsychiatric disease and treatment, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.0field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 15 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Article
  4. Review
  5. Neuroadaptive Biochemical Mechanisms of Remote Ischemic Conditioning.International journal of molecular sciences · 2023
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Chen Qin *Department of Neurology, The First Hospital of Jilin University, Changchun 130021, People's Republic of China.
Xiuli Yan *Department of Neurology, The First Hospital of Jilin University, Changchun 130021, People's Republic of China.
Hang JinDepartment of Neurology, The First Hospital of Jilin University, Changchun 130021, People's Republic of China.
Ruyi ZhangDepartment of Cardiovascular Center, The First Hospital of Jilin University, Changchun 130021, People's Republic of China.
Yaode HeDepartment of Neurology, The First Hospital of Jilin University, Changchun 130021, People's Republic of China.ORCID 0000-0003-3616-6769
Xin SunDepartment of Neurology, The First Hospital of Jilin University, Changchun 130021, People's Republic of China.
Yihe ZhangDepartment of Neurology, The First Hospital of Jilin University, Changchun 130021, People's Republic of China.
Zhen-Ni GuoDepartment of Neurology, The First Hospital of Jilin University, Changchun 130021, People's Republic of China.
Yi YangDepartment of Neurology, The First Hospital of Jilin University, Changchun 130021, People's Republic of China.
Jilin University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ischemic stroke is one of the most common cerebrovascular diseases and is the leading cause of disability all over the world. It is well known that cerebral blood flow (CBF) is disturbed or even disrupted when ischemic stroke happens. The imbalance between demand and shortage of blood supply makes ischemic stroke take place or worsen. The search for treatments that can preserve CBF, especially during the acute phase of ischemic stroke, has become a research hotspot. Animal and clinical experiments have proven that remote ischemic conditioning (RIC) is a beneficial therapeutic strategy for the treatment of ischemic stroke. However, the mechanism by which RIC affects CBF has not been fully understood. This review aims to discuss several possible mechanisms of RIC on the cerebral hemodynamics in ischemic stroke, such as the improvement of cardiac function and collateral circulation of cerebral vessels, the protection of neurovascular units, the formation of gas molecules, the effect on the function of vascular endothelial cells and the nervous system. RIC has the potential to become a therapeutic treatment to improve CBF in ischemic stroke. Future studies are needed to highlight our understanding of RIC as well as accelerate its clinical translation.

Indexed as

cerebral blood flowcerebral hemodynamicsischemic strokeremote ischemic conditioning

Identifiers

PMID32021218
PMCPMC6988382
OpenAlexW3003017606

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.