Evidence map›Paper›PMID 32021180›Full record

ReviewInternational journal of nanomedicine2020

Recent Developments in the Facile Bio-Synthesis of Gold Nanoparticles (AuNPs) and Their Biomedical Applications.

Kar Xin Lee, Kamyar Shameli, Yen Pin Yew, Sin-Yeang Teow, Hossein Jahangirian, Roshanak Rafiee-Moghaddam, Thomas J Webster

Abstract readReview
In one paragraph

Review in International journal of nanomedicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 134 papers.

0numbers the graph read from it
0cells of the map it votes in
134citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

134 citing papers in PubMed.

  1. Dodonaea viscosa-derived gold nanoparticles exhibit differential effects across breast cell models and intracellular localisation in MDA-MB-231 cells.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2026
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  18. Pharmaceutics · 2025
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74 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Kar Xin LeeDepartment of Environmental Engineering and Green Technology, Malaysia-Japan International Institute of Technology, Universiti Teknologi Malaysia, Kuala Lumpur 54100, Malaysia.
Kamyar ShameliDepartment of Environmental Engineering and Green Technology, Malaysia-Japan International Institute of Technology, Universiti Teknologi Malaysia, Kuala Lumpur 54100, Malaysia.
Yen Pin YewDepartment of Environmental Engineering and Green Technology, Malaysia-Japan International Institute of Technology, Universiti Teknologi Malaysia, Kuala Lumpur 54100, Malaysia.
Sin-Yeang TeowDepartment of Medical Sciences, School of Healthcare and Medical Sciences (SHMS), Sunway University, Jalan Universiti, Bandar Sunway 47500, Selangor Darul Ehsan, Malaysia.ORCID 0000-0002-3824-0224
Hossein JahangirianDepartment of Chemical Engineering, 313 Snell Engineering Center, Northeastern University, Boston, MA, USA.ORCID 0000-0001-7035-1963
Roshanak Rafiee-MoghaddamDepartment of Chemical Engineering, 313 Snell Engineering Center, Northeastern University, Boston, MA, USA.ORCID 0000-0002-1571-9822
Thomas J WebsterDepartment of Chemical Engineering, 313 Snell Engineering Center, Northeastern University, Boston, MA, USA.ORCID 0000-0002-2028-5969

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gold nanoparticles (AuNPs) are extensively studied nanoparticles (NPs) and are known to have profound applications in medicine. There are various methods to synthesize AuNPs which are generally categorized into two main types: chemical and physical synthesis. Continuous efforts have been devoted to search for other more environmental-friendly and economical large-scale methods, such as environmentally friendly biological methods known as green synthesis. Green synthesis is especially important to minimize the harmful chemical and toxic by-products during the conventional synthesis of AuNPs. Green materials such as plants, fungi, microorganisms, enzymes and biopolymers are currently used to synthesize various NPs. Biosynthesized AuNPs are generally safer for use in biomedical applications since they come from natural materials themselves. Multiple surface functionalities of AuNPs allow them to be more robust and flexible when combined with different biological assemblies or modifications for enhanced applications. This review focuses on recent developments of green synthesized AuNPs and discusses their numerous biomedical applications. Sources of green materials with successful examples and other key parameters that determine the functionalities of AuNPs are also discussed in this review.

Indexed as

AnimalsBacteriaDrug Delivery SystemsFungiGoldGreen Chemistry TechnologyHumansMetal NanoparticlesNADPhenolsPlantsProteinsTerpenesGoldNADPhenolsProteinsTerpenesAuNPsbiomedical applicationsbiosynthesisgold nanoparticlesgreen materials

Identifiers

PMID32021180
PMCPMC6970630

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.