Evidence map›Paper›PMID 32021172›Full record

ArticleInternational journal of nanomedicine2020

Novel Silver-Platinum Nanoparticles for Anticancer and Antimicrobial Applications.

Aida López Ruiz, Caterina Bartomeu Garcia, Sandra Navarro Gallón, Thomas J Webster

Open access · goldAbstract read
In one paragraph

Article in International journal of nanomedicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 53 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 3 countries.

Aida López RuizDepartment of Chemical Engineering, Universitat Rovira i Virgili, Tarragona, Spain.
Caterina Bartomeu GarciaDepartment of Chemical Engineering, Northeastern University, Boston, MA, USA.
Sandra Navarro GallónDepartment of Chemical Engineering, Northeastern University, Boston, MA, USA.
Thomas J WebsterDepartment of Chemical Engineering, Northeastern University, Boston, MA, USA.ORCID 0000-0002-2028-5969
Northeastern University · USUniversitat Rovira i Virgili · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCancer is a disease with an enormous worldwide impact. One of the fatal complications in cancer patients are bacterial opportunistic infections. The use of chemotherapeutic drugs made cancer remission more frequent and prolonged patient survival, but, increased the risk of infections. PURPOSE: Address the current problem with growing pandemic cancer and considering high risks of complications with bacterial infections, the present study synthesized novel dendritic assembly of silver (Ag)-platinum (Pt) nanoparticles.

methodsNanoparticles were characterized by TEM analysis, and the composition was confirmed by EDX. Bacterial studies were performed for Gram-positive

resultsThe TEM analysis of silver-platinum (AgPt) nanoparticles showed dendrimer shape nanoparticles with a mean size of 42 ± 11nm. Elemental composition was analyzed by EDX, confirming the presence of both Ag and Pt metals. The synthesized nanoparticles significantly inhibited the growth of medically important pathogenic, Gram-positive

conclusionThe newly synthesized AgPt nanoparticles have a promising future as a potent anticancer agent with antibacterial properties.

Indexed as

Antibiotics, AntineoplasticCell Line, TumorDose-Response Relationship, DrugDrug Resistance, Multiple, BacterialEscherichia coliGlioblastomaHumansMelanomaMetal NanoparticlesMicrobial Sensitivity TestsPlatinumPseudomonas aeruginosaSilverStaphylococcus aureusAntibiotics, AntineoplasticPlatinumSilveranticancerantimicrobialmulti-drug resistant bacteriananoparticlesplatinumsilver

Identifiers

PMID32021172
PMCPMC6970512
OpenAlexW2999524581

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.