ArticleClinical interventions in aging2019
Reduced Vitamin D Levels are Associated with Stroke-Associated Pneumonia in Patients with Acute Ischemic Stroke.
Article in Clinical interventions in aging, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.
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Who cites it
15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 24 citations in OpenAlex.
- Procalcitonin and biomarkers for stroke-associated pneumonia: a systematic review and meta-analysis.BMC pulmonary medicine · 2025Pooled it
- Vitamin D supplementation for prevention of acute respiratory infections in older adults: A systematic review and meta-analysis.PloS one · 2024Pooled it
- Advances in stroke-associated pneumonia in the era of revascularization therapy.Chinese medical journal · 2026Review
- Clinical utility of the mini nutritional assessment short form in predicting stroke-associated pneumonia in acute stroke patients: a prospective cohort study.Scientific reports · 2026Article
- Formononetin Protects Against Cerebral Ischemia-Reperfusion-Induced Lung Injury: Insights from Animal and Cell Models.Journal of inflammation research · 2026Article
- Vitamin D deficiency and risk of acute kidney injury after ischemic stroke: a propensity-matched cohort study.Frontiers in nutrition · 2025Article
- Dietary patterns and micronutrients in respiratory infections including COVID-19: a narrative review.BMC public health · 2024Review
- Association between Vitamin D and Short-Term Functional Outcomes in Acute Ischemic Stroke.Nutrients · 2023Article
- Association of Long Non-Coding RNA Malat1 with Serum Levels of Interleukin-1 Beta and Vitamin D in Patients with Ischemic Stroke.Galen medical journal · 2023Article
- Serum Calcium Levels and in-Hospital Infection Risk in Patients with Acute Ischemic Stroke.Neuropsychiatric disease and treatment · 2022Article
- Stroke-induced immunosuppression: implications for the prevention and prediction of post-stroke infections.Journal of neuroinflammation · 2021Review
- Some Comments for Better Understanding of the Study Entitled "Reduced Vitamin D Levels are Associated with Stroke-Associated Pneumonia in Patients with Acute Ischemic Stroke" [Letter].Clinical interventions in aging · 2020Article
- Risk Factors of Vitamin D Deficiency in Chinese Ischemic Stroke Patients: A Cross-Sectional Study.Frontiers in aging neuroscience · 2020Article
- Association of Low Leptin with Poor 3-Month Prognosis in Ischemic Stroke Patients with Type 2 Diabetes.Clinical interventions in aging · 2020Observational
- High Monocyte-To-Lymphocyte Ratio Is Associated With Stroke-Associated Pneumonia.Frontiers in neurology · 2020Article
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8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
aimStroke-associated pneumonia (SAP) is a common complication in patients with acute ischemic stroke (AIS). This study explored the potential relationship between serum vitamin D levels and SAP.
methodsThis study recruited 863 consecutive AIS patients. In-hospital SAP was defined as a complication that occurred after stroke, during hospitalization, that was confirmed radiographically. Serum vitamin D levels were measured within 24 hrs of admission and the patients were divided into vitamin D sufficient (>50 nmol/L), insufficient (25-50 nmol/L), and deficient (<25 nmol/L) groups.
resultsIn this study, 102 (11.8%) patients were diagnosed with SAP. Compared to the patients without SAP, patients with SAP had significantly lower vitamin D levels (P = 0.023). The incidence of SAP was significantly higher in patients with vitamin D deficiency than in those with vitamin D insufficiency or sufficiency (21.2% vs 16.2% & 9.5%, P = 0.006). After adjusting for confounders, vitamin D deficiency and insufficiency were independently associated with SAP (OR = 3.034, 95% CI = 1.207-7.625, P = 0.018; OR = 1.921, 95% CI = 1.204-3.066, P = 0.006, respectively). In multiple-adjusted spline regression, vitamin D levels showed a linear association with the risk of SAP (P < 0.001 for linearity).
conclusionReduced vitamin D is a potential risk factor of in-hospital SAP, which can help clinicians identify high-risk SAP patients.
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