ReviewAnnals of intensive care2020
Ventilatory support and mechanical properties of the fibrotic lung acting as a "squishy ball".
Review in Annals of intensive care, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
30 citing papers in PubMed, 52 citations in OpenAlex.
- Modeling ventilation heterogeneity in lung fibrosis.Medical & biological engineering & computing · 2026Article
- [58/m with progressive dyspnea, dry cough and general weakness : Preparation for the medical specialist examination: part 16].Medizinische Klinik, Intensivmedizin und Notfallmedizin · 2026Article
- Oxygenation in acute exacerbation of interstitial lung disease:a nationwide survey.Scientific reports · 2025Article
- Interactive effects of pulmonary pathologies and ventilation modes driving heterogeneous and anisotropic regional strain mechanics.Scientific reports · 2025Article
- Impact of oxygenation strategies on outcome in acute exacerbation of interstitial lung disease.ERJ open research · 2025Article
- Management strategies and outcomes predictors of interstitial lung disease exacerbation admitted to an intensive care setting: A narrative review.Journal of critical care medicine (Universitatea de Medicina si Farmacie din Targu-Mures) · 2025Review
- Invasive Pleural Manometry to Explore the Physiology Behind Paradoxical Compliance Response to Abdominal Compression-A Case of "Unexpandable" Lung in Acute Respiratory Distress Syndrome.Critical care explorations · 2025Article
- The use of mechanical ventilation in interstitial lung disease.Breathe (Sheffield, England) · 2025Review
- The Link Between Sleep-Related Breathing Disorders and Idiopathic Pulmonary Fibrosis: Pathophysiological Mechanisms and Treatment Options-A Review.Journal of clinical medicine · 2025Review
- Risk factors and management of lung cancer in idiopathic pulmonary fibrosis: A comprehensive review.Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG · 2025Article
- Modeling ventilation of patients with interstitial lung disease at rest and exercise: a bench study.BMC pulmonary medicine · 2024Article
- The Management of Interstitial Lung Disease in the ICU: A Comprehensive Review.Journal of clinical medicine · 2024Review
- Quantitative CT-analysis of over aerated lung tissue and correlation with fibrosis extent in patients with idiopathic pulmonary fibrosis.Respiratory research · 2024Article
- Stress-strain curve and elastic behavior of the fibrotic lung with usual interstitial pneumonia pattern during protective mechanical ventilation.Scientific reports · 2024Article
- Physiological effects of lung-protective ventilation in patients with lung fibrosis and usual interstitial pneumonia pattern versus primary ARDS: a matched-control study.Critical care (London, England) · 2023Article
- Hospital-level variation in practices and outcomes for patients with severe acute exacerbations of idiopathic pulmonary fibrosis: a retrospective multicentre cohort study.BMJ open respiratory research · 2023Article
- Diseased and healthy murine local lung strains evaluated using digital image correlation.Scientific reports · 2023Article
- Systemic sclerosis. Part II: perioperative considerations.BJA education · 2023Review
- A model-based approach to generating annotated pressure support waveforms.Journal of clinical monitoring and computing · 2022Article
- The Mechanism and Regulation of the NLRP3 Inflammasome during Fibrosis.Biomolecules · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
15 authors at 6 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Protective ventilation is the cornerstone of treatment of patients with the acute respiratory distress syndrome (ARDS); however, no studies have yet established the best ventilatory strategy to adopt when patients with acute exacerbation of interstitial lung disease (AE-ILD) are admitted to the intensive care unit. Due to the severe impairment of the respiratory mechanics, the fibrotic lung is at high risk of developing ventilator-induced lung injury, regardless of the lung fibrosis etiology. The purpose of this review is to analyze the effects of mechanical ventilation in AE-ILD and to increase the knowledge on the characteristics of fibrotic lung during artificial ventilation, introducing the concept of "squishy ball lung". The role of positive end-expiratory pressure is discussed, proposing a "lung resting strategy" as opposed to the "open lung approach". The review also discusses the practical management of AE-ILD patients discussing illustrative clinical cases.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.