Evidence map›Paper›PMID 32020404›Full record

ArticleEuropean radiology2020

Potential value of CT radiomics in the distinction of intestinal-type gastric adenocarcinomas.

Yue Wang, Wei Liu, Yang Yu, Wei Han, Jing-Juan Liu, Hua-Dan Xue, Jing Lei, Zheng-Yu Jin, Jian-Chun Yu

Abstract read
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In one paragraph

Article in European radiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Trial
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  11. Development and Validation of a Random Forest Risk Prediction Pneumothorax Model in Percutaneous Transthoracic Needle Biopsy.Medical science monitor : international medical journal of experimental and clinical research · 2021
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  16. Radiotherapy benefited the survival of patients with intestinal-type gastric adenocarcinoma: a SEER population-based study.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yue WangDepartment of Radiology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, No. 1, Shuaifuyuan, Dongcheng District, Bejing, 100730, People's Republic of China.
Wei LiuDepartment of Radiology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, No. 1, Shuaifuyuan, Dongcheng District, Bejing, 100730, People's Republic of China.
Yang YuCT Collaboration, Siemens Healthineers Ltd, 59# Beizhan Road, Shenyang, 110013, People's Republic of China.
Wei HanDepartment of Epidemiology and Biostatistics, Institute of Basic Medical Sciences, School of Basic Medicine, Chinese Academy of Medical Sciences, Peking Union Medical College, No. 5, Dongdansantiao Street, Beijing, 100005, People's Republic of China.
Jing-Juan LiuDepartment of Radiology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, No. 1, Shuaifuyuan, Dongcheng District, Bejing, 100730, People's Republic of China.
Hua-Dan XueDepartment of Radiology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, No. 1, Shuaifuyuan, Dongcheng District, Bejing, 100730, People's Republic of China.
Jing LeiDepartment of Radiology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, No. 1, Shuaifuyuan, Dongcheng District, Bejing, 100730, People's Republic of China.
Zheng-Yu JinDepartment of Radiology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, No. 1, Shuaifuyuan, Dongcheng District, Bejing, 100730, People's Republic of China. jinzy@pumch.cn.
Jian-Chun YuDepartment of General Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, No. 1, Shuaifuyuan, Dongcheng District, Beijing, 100730, People's Republic of China. yu-jch@163.com.ORCID http://orcid.org/0000-0002-8250-7475

Funding

National Public Welfare Basic Scientific Research Program of Chinese Academy of Medical Sciences 2017PT32004National Public Welfare Basic Scientific Research Program of Chinese Academy of Medical Sciences 2018PT32003
6 · The paper itself

Abstract

objectiveThe purpose of the study was to investigate the role of CT radiomics for the preoperative distinction of intestinal-type gastric adenocarcinomas. MATERIALS AND

methodsA total of 187 consecutive patients with preoperative contrast CT examination and pathologically proven gastric adenocarcinoma were retrospectively collected. Patients were divided into a training set (n = 150) and a test set (n = 37). Arterial phase (AP), portal phase (PP), and delay phase (DP) images were retrieved for analysis. A dedicated postprocessing software was used to segment the lesions and extract radiomics features. Random forest (RF) algorithm was applied to construct the classifier models. A nomogram was developed by incorporating multiphase radiomics scores. Receiver operating characteristic (ROC) curves were used to evaluate the performance of the radiomics model and nomogram in both sets.

resultsThe radiomics model showed a favorable capability in the distinction of intestinal-type gastric adenocarcinomas. The areas under curves (AUCs) of the AP, PP, and DP radiomics models were 0.754 (95% CI: 0.676, 0.820), 0.815 (95% CI: 0.744, 0.874), and 0.764 (95% CI: 0.688, 0.829) in the training set, respectively, which were confirmed in the test set with AUCs of 0.742 (95% CI: 0.572, 0.872), 0.775 (95% CI: 0.608, 0.895), and 0.857 (95% CI: 0.703, 0.950), respectively. The nomogram yielded excellent performance for distinguishing intestinal-type adenocarcinomas in both sets, with AUCs of 0.928 (95%: 0.875, 0.964) and 0.904 (95% CI: 0.761, 0.976).

conclusionsThe multiphase CT radiomics nomogram holds promise for the individual preoperative discrimination of intestinal-type gastric adenocarcinoma. KEY POINTS: • CT radiomics has a potential role in the distinction of intestinal-type gastric adenocarcinomas. • Single-phase enhanced CT-based radiomics showed favorable capability in distinguishing intestinal-type tumors. • The nomogram which incorporates the multiphase radiomics scores could facilitate the individual prediction of intestinal-type lesions.

Indexed as

AdenocarcinomaAdultAgedAged, 80 and overAlgorithmsArea Under CurveFemaleHumansMaleMiddle AgedNomogramsPreoperative PeriodRetrospective StudiesROC CurveSoftwareStomach NeoplasmsGastric cancerNomogramPathology

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.