Evidence map›Paper›PMID 32020325›Full record

ArticleWorld journal of surgery2020

Concordance Study in Hepatectomy Recommendations Between Watson for Oncology and Clinical Practice for Patients with Hepatocellular Carcinoma in China.

Weiqi Zhang, Shuo Qi, Jiaming Zhuo, Sai Wen, Chihua Fang

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Article in World journal of surgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

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6citing papers in PubMed, 1 pooled it
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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Weiqi ZhangGuangdong Provincial Clinical and Engineering Center of Digital Medicine, The First Department of Hepatobiliary Surgery Zhujiang Hospital, Southern Medical University, Guangzhou, 510282, China.
Shuo QiGuangdong Provincial Clinical and Engineering Center of Digital Medicine, The First Department of Hepatobiliary Surgery Zhujiang Hospital, Southern Medical University, Guangzhou, 510282, China.
Jiaming ZhuoGuangdong Provincial Clinical and Engineering Center of Digital Medicine, The First Department of Hepatobiliary Surgery Zhujiang Hospital, Southern Medical University, Guangzhou, 510282, China.
Sai WenGuangdong Provincial Clinical and Engineering Center of Digital Medicine, The First Department of Hepatobiliary Surgery Zhujiang Hospital, Southern Medical University, Guangzhou, 510282, China.
Chihua FangGuangdong Provincial Clinical and Engineering Center of Digital Medicine, The First Department of Hepatobiliary Surgery Zhujiang Hospital, Southern Medical University, Guangzhou, 510282, China. fangch_dr@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWith the improvement in diagnostic imaging, perioperative care and surgical technique, the indications and complexity of liver resections have developed. However, the surgical indications remain controversial especially for some complex or advanced hepatocellular carcinomas. This study was designed to evaluate the concordance between hepatectomy recommendations proposed by Watson for Oncology, a cognitive technology providing decision support, and those determined by surgeons in our center for patients with hepatocellular carcinoma.

methodsWe retrospectively reviewed 243 patients with hepatocellular carcinoma who were recommended for surgical treatment and received hepatectomy between 2008 and 2016 at the Zhujiang Hospital of Southern Medical University. Watson for Oncology classified the treatment options into three categories: recommended, for consideration and not recommended. Treatment recommendations were considered concordant if the hepatectomy recommendations were designated "recommended" or "for consideration" by Watson for Oncology. The factors potentially affecting concordance rate were also analyzed in our study.

resultsThe hepatectomy recommendations of 174 patients were concordant. There were significant differences in the coincidence rate between concordant group and discordant group considering tumor numbers (P = 0.006), extension of hepatectomy (P = 0.009) and BCLC staging system (P < 0.001). Lower degrees of concordance were observed in patients with multiple tumors, major hepatectomy and portal hypertension by using logistic regression analysis (OR = 0.309, P = 0.004; OR = 0.384, P = 0.004; and OR = 0.376, P = 0.022, respectively).

conclusionThe concordance between Watson for Oncology and surgeons' hepatectomy recommendation for hepatocellular carcinoma was only 72%. Differences in practice patterns for HCC between the USA (where Watson for Oncology was calibrated) and China may be the major cause of discordance. Watson for Oncology still requires further improvement and localization to be widely applied in China.

Indexed as

Artificial IntelligenceDecision Support Systems, ClinicalMedical OncologyAdultAgedCarcinoma, HepatocellularFemaleHepatectomyHumansLiver NeoplasmsMaleMiddle AgedRetrospective Studies

Identifiers

PMID32020325

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.