Evidence map›Paper›PMID 32020293›Full record

ArticleJournal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry2020

The interactions of the ruthenium(II)-cymene complexes with lysozyme and cytochrome c.

Dragana Stanic-Vucinic, Stefan Nikolic, Katarina Vlajic, Mirjana Radomirovic, Jelena Mihailovic, Tanja Cirkovic Velickovic, Sanja Grguric-Sipka

Open access · greenAbstract read
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In one paragraph

Article in Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 3 countries.

Dragana Stanic-VucinicFaculty of Chemistry, Center of Excellence for Molecular Food Sciences, Department of Biochemistry, University of Belgrade, Studentski trg 12-16, 11000, Belgrade, Serbia.ORCID http://orcid.org/0000-0003-2576-3074
Stefan NikolicInnovation Center of the Faculty of Chemistry, University of Belgrade, Studentski trg 12-16, 11000, Belgrade, Serbia.ORCID http://orcid.org/0000-0002-0164-134X
Katarina VlajicFaculty of Chemistry, Center of Excellence for Molecular Food Sciences, Department of Biochemistry, University of Belgrade, Studentski trg 12-16, 11000, Belgrade, Serbia.
Mirjana RadomirovicFaculty of Chemistry, Center of Excellence for Molecular Food Sciences, Department of Biochemistry, University of Belgrade, Studentski trg 12-16, 11000, Belgrade, Serbia.
Jelena MihailovicFaculty of Chemistry, Center of Excellence for Molecular Food Sciences, Department of Biochemistry, University of Belgrade, Studentski trg 12-16, 11000, Belgrade, Serbia.ORCID http://orcid.org/0000-0003-0562-0447
Tanja Cirkovic VelickovicFaculty of Chemistry, Center of Excellence for Molecular Food Sciences, Department of Biochemistry, University of Belgrade, Studentski trg 12-16, 11000, Belgrade, Serbia.ORCID http://orcid.org/0000-0003-2559-5234
Sanja Grguric-SipkaFaculty of Chemistry, Department of Inorganic Chemistry, University of Belgrade, Studentski trg 12-16, 11000, Belgrade, Serbia. sanjag@chem.bg.ac.rs.ORCID http://orcid.org/0000-0003-1906-535X
University of Belgrade · RSSerbian Academy of Sciences and Arts · RS

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The reactions of four cymene-capped ruthenium(II) compounds with pro-apoptotic protein, cytochrome c (Cyt), and anti-proliferative protein lysozyme (Ly) in carbonate buffer were investigated by ESI-MS, UV-vis absorption, and CD spectroscopy. The complexes with two chloride ligands (C2 and C3) were more reactive toward proteins than those with only one (C1 and C4), and the complex with S,N-chelating ligand (C4) was less reactive than one with O,N-chelating ligand (C1). Dehalogenated complexes are most likely species, initially coordinating proteins for all tested complexes. During the time, protein adducts vividly exchanged non-arene organic ligand L with CO

Indexed as

Coordination ComplexesCymenesCytochromes cMolecular ConformationMuramidaseRutheniumCoordination ComplexesCymenesCytochromes cMuramidaseRutheniumAnticancer metallodrugsMass spectrometryProtein metalationRuthenium(II)-cymene complexes

Identifiers

PMID32020293
OpenAlexW3005472179

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.