Trial reportSurgical endoscopy2020
A new method of near-infrared fluorescence image-guided hepatectomy for patients with hepatolithiasis: a randomized controlled trial.
Trial report in Surgical endoscopy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 30 citations in OpenAlex.
- Efficacy of Near-Infrared Fluorescence Video-Assisted Thoracoscopic Surgery for Small Pulmonary Nodule Resection with Indocyanine Green Inhalation: A Randomized Clinical Trial.Annals of surgical oncology · 2023Trial
- Tumor lesion detection in patients with cervical cancer by indocyanine green near-infrared imaging.European journal of nuclear medicine and molecular imaging · 2023Trial
- Intraoperative near-infrared fluorescence imaging can identify pelvic nerves in patients with cervical cancer in real time during radical hysterectomy.European journal of nuclear medicine and molecular imaging · 2022Trial
- Near-infrared fluorescence imaging improves biliary visualization and perioperative outcomes in difficult laparoscopic cholecystectomy: implications for future clinical studies.Surgical endoscopy · 2026Article
- Application of three-dimensional visualization technology on one-step PTCSL for complex hepatolithiasis.Updates in surgery · 2026Article
- Laparoscopic hepatectomy and near-infrared fluorescence based on the concept of "biliary territory" in the treatment of hepatolithiasis: a propensity score-matched study with videos.Hepatobiliary surgery and nutrition · 2025Article
- Review
- Harmonized technical standard test methods for quality evaluation of medical fluorescence endoscopic imaging systems.Visual computing for industry, biomedicine, and art · 2025Article
- Preliminary exploration of hepatic parenchymal near-infrared fluorescence imaging technique via retrograde biliary approach: a feasibility study (with video).Scientific reports · 2024Article
- Does Using Indocyanine Green Fluorescence Imaging for Tumors Help in Determining the Safe Surgical Margin in Real-Time Navigation of Laparoscopic Hepatectomy? A Retrospective Study.Annals of surgical oncology · 2023Article
- Preoperative 3D reconstruction and fluorescent indocyanine green for laparoscopic duodenum preserving pancreatic head resection: A case report.World journal of clinical cases · 2023Article
- Intraoperative fluorescence molecular imaging accelerates the coming of precision surgery in China.European journal of nuclear medicine and molecular imaging · 2022Review
- Essential updates 2020/2021: Current topics of simulation and navigation in hepatectomy.Annals of gastroenterological surgery · 2022Review
- Laparoscopic middle-hepatic-vein-guided anatomical hemihepatectomy in the treatment of hepatolithiasis: a 10-year case study.Surgical endoscopy · 2022Article
- Assessing the development status of intraoperative fluorescence imaging for anatomy visualisation, using the IDEAL framework.BMJ surgery, interventions, & health technologies · 2022Article
- Article
- Indocyanine green fluorescence navigation in laparoscopic hepatectomy: a retrospective single-center study of 120 cases.Surgery today · 2021Article
- Indocyanine green and its nanosynthetic particles for the diagnosis and treatment of hepatocellular carcinoma.American journal of translational research · 2020Review
Corrections and comments
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Authors and funding
10 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundHepatectomy is a definitive treatment for hepatolithiasis because it simultaneously removes intrahepatic duct (IHD) stones and biliary tract strictures together with the involved liver region en bloc. Unlike cystic or solid liver tumors, hepatolithiasis is usually associated with alterations of anatomical structures and perihepatic adhesions because of chronic recurrent inflammation. This complicates identification of the target hepatic region and location of biliary strictures.
methodsTo determine the efficacy of near-infrared fluorescence (NIRF) imaging using indocyanine green (ICG), we performed a comparative trial and developed a white-light and near-infrared dual-channel image-guided device (DPM-I) for both open and endoscopic surgery. Forty-four eligible patients were randomly assigned to Group A (NIRF imaging) or Group B (traditional hepatectomy). We injected ICG via peripheral veins for patients in Group A.
resultsThe NIRF imaging method was associated with less blood loss (OR 1.004, 95% CI 0.999-1.010; P = 0.016), briefer hospitalization (OR 1.336, 95% CI 1.016-1.756; P = 0.001), lower rates of margins with dilated bile ducts (OR 1.278, 95% CI 1.030-1.585; P = 0.023), lower postoperative white blood cell counts (OR 1.262, 95% CI 0.931-1.712; P = 0.038), lower procalcitonin levels (OR 1.316, 95% CI 1.020-1.513; P = 0.002), and lower alanine aminotransferase levels (OR 1.013, 95% CI 1.003-1.023; P = 0.002) compared with traditional hepatectomy.
conclusionsThese data demonstrate the efficacy of NIRF imaging with ICG using DPM-I for treating hepatolithiasis.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.