Evidence map›Paper›PMID 32019767›Full record

ArticleJournal of investigative medicine : the official publication of the American Federation for Clinical Research2020

Monica Ceol, Lisa Gianesello, Enrica Tosetto, Giovanna Priante, Dorella Del Prete, Franca Anglani

Open access · greenAbstract read
In one paragraph

Article in Journal of investigative medicine : the official publication of the American Federation for Clinical Research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 57% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Monica Ceol *Kidney Histomorphology and Molecular Biology Laboratory, Clinical Nephrology Unit, Department of Medicine-DIMED, University of Padua, Padua, Italy monica.ceol@unipd.it.ORCID 0000-0001-7489-2433
Lisa Gianesello *Kidney Histomorphology and Molecular Biology Laboratory, Clinical Nephrology Unit, Department of Medicine-DIMED, University of Padua, Padua, Italy.ORCID 0000-0001-9327-397X
Enrica TosettoKidney Histomorphology and Molecular Biology Laboratory, Clinical Nephrology Unit, Department of Medicine-DIMED, University of Padua, Padua, Italy.
Giovanna PrianteKidney Histomorphology and Molecular Biology Laboratory, Clinical Nephrology Unit, Department of Medicine-DIMED, University of Padua, Padua, Italy.ORCID 0000-0002-1870-4466
Dorella Del PreteKidney Histomorphology and Molecular Biology Laboratory, Clinical Nephrology Unit, Department of Medicine-DIMED, University of Padua, Padua, Italy.ORCID 0000-0003-2141-3472
Franca AnglaniKidney Histomorphology and Molecular Biology Laboratory, Clinical Nephrology Unit, Department of Medicine-DIMED, University of Padua, Padua, Italy.ORCID 0000-0003-1534-4458
University of Padua · IT

Funding

Primary HyperoxaluriaU54DK083908 · NIDDK · MAYO CLINIC ROCHESTER · PI MILLINER, DAWN SCHMAUTZ · 2009 to 2018
$12.3M
NIDDK NIH HHS U54 DK083908
6 · The paper itself

Abstract

ClC-5, the electrogenic chloride/proton exchanger strongly expressed in renal proximal tubules, belongs to the endocytic macromolecular complex responsible for albumin and low-molecular-weight protein uptake. ClC-5 was found to be overexpressed in glomeruli of glomerulonephritis and in cultured human podocytes under albumin overload. The transcriptional regulation of human ClC-5 is not fully understood. Three functional promoters of various strengths and 11 different 5' untranslated region (5'UTR) isoforms of

Indexed as

Gene Expression Regulation5' Untranslated RegionsAgedBiopsyCase-Control StudiesChloride ChannelsFemaleGene Expression ProfilingGlomerulonephritisHumansKidneyMaleMiddle AgedProtein Isoforms5' Untranslated RegionsChloride ChannelsCLC-5 chloride channelProtein Isoforms5’UTRCLCN5gene expressionisoformsproteinuria

Identifiers

PMID32019767
PMCPMC7402611
OpenAlexW3004790939

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.