ArticleEpidemiology and infection2020
Article in Epidemiology and infection, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 22 citations in OpenAlex.
- The association of the advanced lung cancer inflammation index with the risk ofFrontiers in cellular and infection microbiology · 2026Article
- Association betweenFrontiers in nutrition · 2026Article
- Immune responses to infection and autoimmune diseases in the UK biobank.Journal of translational autoimmunity · 2025Article
- Association between non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio and Helicobacter pylori infection.Scientific reports · 2025Article
- Accelerated biological aging mediates the association between inflammatory markers with Helicobacter pylori infection and mortality.Journal of translational medicine · 2025Article
- Triglyceride-glucose index and mortality risks in Helicobacter pylori-infected patients: a national cohort study.BMC infectious diseases · 2025Article
- Association between non-insulin-based insulin resistance surrogate makers and Helicobacter pylori infection: a population-based study.BMC gastroenterology · 2025Article
- Evaluating the relationship between familial poverty,Frontiers in public health · 2025Article
- Analysis between Helicobacter pylori infection and hepatobiliary diseases.Frontiers in cellular and infection microbiology · 2025Article
- Article
- Association betweenFrontiers in endocrinology · 2025Article
- Relationships among Helicobacter pylori seropositivity, the triglyceride-glucose index, and cardiovascular disease: a cohort study using the NHANES database.Cardiovascular diabetology · 2024Article
- Association of oxidative balance score with Helicobacter pylori infection and mortality among US population.European journal of nutrition · 2024Article
- Additive impact of diabetes and Helicobacter pylori infection on all-cause mortality, diabetic mortality, and cardiovascular mortality: a longitudinal nationwide population-based study.Diabetology & metabolic syndrome · 2024Article
- Obesity, abdominal obesity, metabolic obesity phenotypes, and Helicobacter pylori infection: results from NHANES 1999-2000.BMC infectious diseases · 2024Article
- Association of dietary inflammatory index with helicobacter pylori infection and mortality among US population.Journal of translational medicine · 2023Article
- Atrophic Gastritis and Autoimmunity: Results from a Prospective, Multicenter Study.Diagnostics (Basel, Switzerland) · 2023Article
- Association between serum vitamin D levels andBMJ open · 2022Article
- Association betweenFrontiers in endocrinology · 2022Article
- Hygiene Hypothesis Indicators and Prevalence of Antinuclear Antibodies in US Adolescents.Frontiers in immunology · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 1 country.
Funding
Abstract
Infectious diseases, such as Helicobacter pylori, which produce systemic inflammation may be one key factor in the onset of autoimmunity. The association between H. pylori and antinuclear antibodies (ANA), a marker of autoimmunity, has been understudied. Data from the 1999-2000 National Health and Nutrition Examination Survey were used to evaluate the cross-sectional association between H. pylori seroprevalence and ANA positivity in US adults aged ≥20 years. ANA was measured in a 1:80 dilution of sera by indirect immunofluorescence using HEp-2 cells (positive ⩾3). H. pylori immunoglobulin G enzyme-linked immunosorbent assays were used to categorise individuals as seropositive or seronegative. H. pylori seropositivity and ANA positivity were common in the adult US population, with estimated prevalences of 33.3% and 9.9%, respectively. Both were associated with increasing age. H. pylori seropositivity was associated with higher odds of ANA (prevalence odds ratio = 1.89, 95% confidence interval = 1.08-3.33), adjusted for age, sex, race/ethnicity, educational attainment and body mass index. H. pylori infection may be one key factor in the loss of self-tolerance, contributing to immune dysfunction.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.