ArticleBMC plant biology2020
Transcriptome analysis reveals insight into molecular hydrogen-induced cadmium tolerance in alfalfa: the prominent role of sulfur and (homo)glutathione metabolism.
Article in BMC plant biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
24 citing papers in PubMed, 70 citations in OpenAlex.
- Article
- Lobularia maritima essential oil modulates heavy-metal transporter expression and mitigates cadmium stress in durum wheat.Protoplasma · 2026Article
- Hydrogen-rich water alleviates cadmium stress in Chinese flowering cabbage by enhancing antioxidant capacity, improving photosynthesis, and reducing cadmium uptake.Frontiers in plant science · 2026Article
- Crosstalk between glutathione and melatonin in chromium detoxification in sweet potato revealed by high-throughput sequencing and physio-biochemical profiling.Frontiers in plant science · 2026Article
- Sulfur Mitigates Cadmium Toxicity in Lettuce via Phytochelatins and the AsA-GSH Cycle.Journal of agricultural and food chemistry · 2025Article
- Molecular Hydrogen Improves Blueberry Main Fruit Traits via Metabolic Reprogramming.Plants (Basel, Switzerland) · 2025Article
- Physiological, transcriptomic, and metabolomic analyses of the chilling stress response in two melon (Cucumis melo L.) genotypes.BMC plant biology · 2024Article
- MODMS: a multi-omics database for facilitating biological studies on alfalfa (Horticulture research · 2024Article
- Regulation of hydrogen rich water on strawberry seedlings and root endophytic bacteria under salt stress.Frontiers in plant science · 2024Article
- Transcriptomic and Functional Analyses of Two Cadmium Hyper-Enriched Duckweed Strains Reveal Putative Cadmium Tolerance Mechanisms.International journal of molecular sciences · 2023Article
- Article
- Exogenous hydrogen sulfide and methylglyoxal alleviate cadmium-induced oxidative stress in Salix matsudana Koidz by regulating glutathione metabolism.BMC plant biology · 2023Article
- Characterization, Expression Profiling, and Biochemical Analyses of theInternational journal of molecular sciences · 2022Article
- Characterization of cadmium accumulation mechanism between eggplant (Frontiers in plant science · 2022Article
- Effects of Cadmium on Root Morpho-Physiology of Durum Wheat.Frontiers in plant science · 2022Article
- Molecular Hydrogen: Is This a Viable New Treatment for Plants in the UK?Plants (Basel, Switzerland) · 2021Review
- Molecular hydrogen in agriculture.Planta · 2021Review
- Hydrogen Nanobubble Water Delays Petal Senescence and Prolongs the Vase Life of Cut Carnation (Plants (Basel, Switzerland) · 2021Article
- Physiology and molecular biology of plants : an international journal of functional plant biology · 2021Article
- Characterisation of manganese toxicity tolerance inPlant diversity · 2021Article
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundHydrogen gas (H
resultsA total of 1968 differentially expressed genes (DEGs) in alfalfa seedling roots under Cd and/or HRW treatment were identified by RNA-Seq. The DEGs were classified into many clusters, including glutathione (GSH) metabolism, oxidative stress, and ATP-binding cassette (ABC) transporters. The results validated by RT-qPCR showed that the levels of relevant genes involved in sulfur metabolism were enhanced by HRW under Cd treatment, especially the genes involved in (homo)glutathione metabolism. Additional experiments carried out with a glutathione synthesis inhibitor and Arabidopsis thaliana cad2-1 mutant plants suggested the prominent role of glutathione in HRW-induced Cd tolerance. These results were in accordance with the effects of HRW on the contents of (homo)glutathione and (homo)phytochelatins and in alleviating oxidative stress under Cd stress. In addition, the HRW-induced alleviation of Cd toxicity might also be caused by a decrease in available Cd in seedling roots, achieved through ABC transporter-mediated secretion.
conclusionsTaken together, the results of our study indicate that H
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.