ArticleJournal of the Royal Society, Interface2020
Fluid and solute transport across the retinal pigment epithelium: a theoretical model.
Article in Journal of the Royal Society, Interface, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 31 citations in OpenAlex.
- Reversal of aqueous flow in myopic, vitrectomized eyes with scleral-fixated intraocular lenses: A proposed mechanism underlying reverse pupillary block.American journal of ophthalmology case reports · 2026Article
- Cellular Biological Basis and Novel Breakthroughs in the Pathogenesis of Myopia - A Narrative Review.International journal of general medicine · 2026Review
- Artificial Intelligence Deep Learning Models to Predict Spaceflight Associated Neuro-Ocular Syndrome.American journal of ophthalmology · 2025Article
- AllJournal of the Royal Society, Interface · 2025Article
- A Model of the Mechanisms Underpinning Unconventional Aqueous Humor Outflow.Investigative ophthalmology & visual science · 2025Article
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- A Mathematical Model of Interstitial Fluid Flow and Retinal Tissue Deformation in Macular Edema.Investigative ophthalmology & visual science · 2024Article
- The Ocular Glymphatic System-Current Understanding and Future Perspectives.International journal of molecular sciences · 2024Review
- Drug Distribution After Intravitreal Injection: A Mathematical Model.Investigative ophthalmology & visual science · 2024Article
- Bilateral macular edema secondary to nab-paclitaxel therapy for breast cancer.International journal of ophthalmology · 2024Article
- Cell-cell interaction in the pathogenesis of inherited retinal diseases.Frontiers in cell and developmental biology · 2024Review
- Volumetric Reconstruction of a Human Retinal Pigment Epithelial Cell Reveals Specialized Membranes and Polarized Distribution of Organelles.Investigative ophthalmology & visual science · 2023Article
- Mechanisms of macular edema.Frontiers in medicine · 2023Review
- A Mathematical Model of Aqueous Humor Production and Composition.Investigative ophthalmology & visual science · 2022Article
- A Splicing Mutation inInternational journal of molecular sciences · 2022Article
- Application of an organotypic ocular perfusion model to assess intravitreal drug distribution in human and animal eyes.Journal of the Royal Society, Interface · 2022Article
Corrections and comments
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Authors and funding
4 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The retina is composed of two main layers-the neuroretina and the retinal pigment epithelium (RPE)-that are separated by a potential gap termed the sub-retinal space (SRS). Accumulation of fluid in the SRS may result in a retinal detachment. A key function of the RPE is to prevent fluid accumulation in the SRS by actively pumping fluid from this space to the choroid. We have developed a mathematical model of this process that incorporates the transport of seven chemical species: Na
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.