Evidence map›Paper›PMID 32019276›Full record

ArticleCells2020

Leucine Improved Growth Performance, Muscle Growth, and Muscle Protein Deposition Through AKT/TOR and AKT/FOXO3a Signaling Pathways in Hybrid Catfish

Ye Zhao, Jin-Yang Li, Qin Jiang, Xiao-Qiu Zhou, Lin Feng, Yang Liu, Wei-Dan Jiang, Pei Wu, Jian Zhou, Juan Zhao and 1 more

Open access · goldAbstract read
In one paragraph

Article in Cells, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
3.1field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 69 citations in OpenAlex.

  1. Leucine regulates the mTOR pathway to improve growth and enhance immune responses inAnimal nutrition (Zhongguo xu mu shou yi xue hui) · 2026
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  9. Aflatoxin B1 decreased flesh flavor and inhibited muscle development in grass carp (Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Ye ZhaoCollege of Animal Science and Technology, Sichuan Agricultural University, Chengdu 611130, China.
Jin-Yang LiCollege of Animal Science and Technology, Sichuan Agricultural University, Chengdu 611130, China.
Qin JiangCollege of Animal Science and Technology, Sichuan Agricultural University, Chengdu 611130, China.
Xiao-Qiu ZhouAnimal Nutrition Institute, Sichuan Agricultural University, Chengdu 611130, China.
Lin FengAnimal Nutrition Institute, Sichuan Agricultural University, Chengdu 611130, China.
Yang LiuAnimal Nutrition Institute, Sichuan Agricultural University, Chengdu 611130, China.
Wei-Dan JiangAnimal Nutrition Institute, Sichuan Agricultural University, Chengdu 611130, China.
Pei WuAnimal Nutrition Institute, Sichuan Agricultural University, Chengdu 611130, China.
Jian ZhouFisheries Institute of Sichuan Academy of Agricultural Science, Chengdu 611731, China.
Juan ZhaoAnimal Nutrition Institute, Sichuan Agricultural University, Chengdu 611130, China.
Jun JiangCollege of Animal Science and Technology, Sichuan Agricultural University, Chengdu 611130, China.
Sichuan Agricultural University · CNSichuan Academy of Agricultural Sciences · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

(1) Background: l-leucine (Leu) plays a positive role in regulating protein turnover in skeletal muscle in mammal. However, the molecular mechanism for the effects of Leu on muscle growth and protein deposition is not clearly demonstrated in fish. This study investigated the effects of dietary Leu on growth performance and muscle growth, protein synthesis, and degradation-related signaling pathways of hybrid catfish (

Indexed as

AnimalsCatfishesCrosses, GeneticDietFemaleForkhead Box Protein O3Gene Expression Regulation, DevelopmentalHybridization, GeneticInsulin-Like Growth Factor ILeucineMaleMuscle DevelopmentMuscle Fibers, SkeletalMuscle ProteinsProteolysisProto-Oncogene Proteins c-aktForkhead Box Protein O3Insulin-Like Growth Factor ILeucineMuscle ProteinsProto-Oncogene Proteins c-aktReceptor, IGF Type 1RNARNA, MessengerTOR Serine-Threonine Kinaseshybrid bagrid catfishleucinemuscle growthprotein degradationprotein synthesis

Identifiers

PMID32019276
PMCPMC7072317
OpenAlexW3003730272

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.