Evidence map›Paper›PMID 32019233›Full record

ArticleMarine drugs2020

Synthesis and Antimicrobial Evaluation of Side-Chain Derivatives based on Eurotiumide A.

Atsushi Nakayama, Hideo Sato, Tenta Nakamura, Mai Hamada, Shuji Nagano, Shuhei Kameyama, Yui Furue, Naoki Hayashi, Go Kamoshida, Sangita Karanjit and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Marine drugs, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Atsushi NakayamaGraduate School of Pharmaceutical Sciences and Research Cluster on "Innovative Chemical Sensing", Tokushima University, 1-78-1 Shomachi, Tokushima 770-8505, Japan.
Hideo SatoGraduate School of Pharmaceutical Sciences and Research Cluster on "Innovative Chemical Sensing", Tokushima University, 1-78-1 Shomachi, Tokushima 770-8505, Japan.
Tenta NakamuraGraduate School of Pharmaceutical Sciences and Research Cluster on "Innovative Chemical Sensing", Tokushima University, 1-78-1 Shomachi, Tokushima 770-8505, Japan.
Mai HamadaGraduate School of Pharmaceutical Sciences and Research Cluster on "Innovative Chemical Sensing", Tokushima University, 1-78-1 Shomachi, Tokushima 770-8505, Japan.
Shuji NaganoGraduate School of Pharmaceutical Sciences and Research Cluster on "Innovative Chemical Sensing", Tokushima University, 1-78-1 Shomachi, Tokushima 770-8505, Japan.
Shuhei KameyamaGraduate School of Pharmaceutical Sciences and Research Cluster on "Innovative Chemical Sensing", Tokushima University, 1-78-1 Shomachi, Tokushima 770-8505, Japan.
Yui FurueDepartment of Microbiology and Infection Control Sciences, Kyoto Pharmaceutical University, Misasaginakauchi-cho, Yamashita-Ku, Kyoto 607-8414, Japan.
Naoki HayashiDepartment of Microbiology and Infection Control Sciences, Kyoto Pharmaceutical University, Misasaginakauchi-cho, Yamashita-Ku, Kyoto 607-8414, Japan.
Go KamoshidaDepartment of Microbiology and Infection Control Sciences, Kyoto Pharmaceutical University, Misasaginakauchi-cho, Yamashita-Ku, Kyoto 607-8414, Japan.
Sangita KaranjitGraduate School of Pharmaceutical Sciences and Research Cluster on "Innovative Chemical Sensing", Tokushima University, 1-78-1 Shomachi, Tokushima 770-8505, Japan.
Masataka OdaDepartment of Microbiology and Infection Control Sciences, Kyoto Pharmaceutical University, Misasaginakauchi-cho, Yamashita-Ku, Kyoto 607-8414, Japan.
Kosuke NambaGraduate School of Pharmaceutical Sciences and Research Cluster on "Innovative Chemical Sensing", Tokushima University, 1-78-1 Shomachi, Tokushima 770-8505, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Side-chain derivatives of eurotiumide A, a dihydroisochroman-type natural product, have been synthesized and their antimicrobial activities described. Sixteen derivatives were synthesized from a key intermediate of the total synthesis of eurotiumide A, and their antimicrobial activities against two Gram-positive bacteria, methicillin-susceptible and methicillin-resistant

Indexed as

Anti-Bacterial AgentsChromansMethicillin-Resistant Staphylococcus aureusPorphyromonas gingivalisStaphylococcus aureusStructure-Activity RelationshipAnti-Bacterial AgentsChromansantibioticsmethicillin-resistant S. aureusnatural productP. gingivalis

Identifiers

PMID32019233
PMCPMC7074549

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.