Evidence map›Paper›PMID 32019222›Full record

Trial reportNutrients2020

Effect of Oral Probiotic

Siwen Yang, Gregor Reid, John R G Challis, Gregory B Gloor, Elizabeth Asztalos, Deborah Money, Shannon Seney, Alan D Bocking

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Nutrients, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed, 5 pooled it
5.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

55 citing papers in PubMed, 5 syntheses or guidelines pooled it, 79 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. The Effect of Exogenous Sex Steroids on the Vaginal Microbiota: A Systematic Review.Frontiers in cellular and infection microbiology · 2021
    Pooled it
  6. Trial
  7. Trial
  8. Nutrients · 2025
    Trial
  9. Trial
  10. Trial
  11. ProbioticFrontiers in cellular and infection microbiology · 2021
    Trial
  12. Article
  13. Review
  14. Microbe on the move:Journal of bacteriology · 2026
    Review
  15. Microorganisms · 2026
    Article
  16. Review
  17. Review
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

Siwen YangDepartments of Physiology and Obstetrics and Gynecology, University of Toronto, Toronto, ON M5G 1E2, Canada.
Gregor ReidDepartments of Microbiology and Immunology, The University of Western Ontario, London, ON N6A 5C1, Canada.
John R G ChallisDepartments of Physiology and Obstetrics and Gynecology, University of Toronto, Toronto, ON M5G 1E2, Canada.
Gregory B GloorLawson Health Research Institute, 268 Grosvenor Street, London, ON N6A 4V2, Canada.
Elizabeth AsztalosDepartment of Newborn & Developmental Paediatrics, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON M5A 1B2, Canada.
Deborah MoneyDepartment of Obstetrics and Gynecology, University of British Columbia, 317-2194 Health Sciences Mall, Vancouver, BC V6T 1Z3, Canada.
Shannon SeneyLawson Health Research Institute, 268 Grosvenor Street, London, ON N6A 4V2, Canada.
Alan D BockingDepartments of Physiology and Obstetrics and Gynecology, University of Toronto, Toronto, ON M5G 1E2, Canada.
University of Toronto · CAWestern University · CALawson Health Research Institute · CASunnybrook Health Science Centre · CAUniversity of British Columbia · CA

Funding

CIHR TBD
6 · The paper itself

Abstract

Spontaneous preterm birth is associated with vaginal microbial dysbiosis. As certain strains of lactobacilli help restore homeostasis in non-pregnant women, the goal was to determine the effect of

Indexed as

Lacticaseibacillus rhamnosusLimosilactobacillus reuteriAdministration, OralAdultChemokinesCytokinesDouble-Blind MethodDysbiosisFemaleHumansMicrobiotaPregnancyPregnancy Complications, InfectiousPremature BirthProbioticsTreatment OutcomeChemokinesCytokinesbacterial vaginosischemokinescytokinesmicrobiotapregnancyprobiotics

Identifiers

PMID32019222
PMCPMC7071157
OpenAlexW3003989000

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.