ArticleInternational journal of molecular sciences2020
Combined Proteomics and Metabolism Analysis Unravels Prominent Roles of Antioxidant System in the Prevention of Alfalfa (
Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed, 62 citations in OpenAlex.
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- Combined analysis of proteomics and metabolism reveals critical roles of oxidoreductase activity in mushrooms stimulated by wolfberry and sea buckthorn substrates.Frontiers in nutrition · 2025Article
- Thriving in a salty future: morpho-anatomical, physiological and molecular adaptations to salt stress in alfalfa (Medicago sativa L.) and other crops.Annals of botany · 2024Review
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- Tandem mass tag (TMT)-based quantitative proteomics analysis reveals the different responses of contrasting alfalfa varieties to drought stress.BMC genomics · 2024Article
- Integrated transcriptome and metabolism unravel critical roles of carbon metabolism and oxidoreductase in mushroom with Korshinsk peashrub substrates.BMC genomics · 2024Article
- Comparative Transcriptome Analysis Reveals Inhibitory Roles of Strigolactone in Axillary Bud Outgrowth in Ratoon Rice.Plants (Basel, Switzerland) · 2024Article
- Elucidation of Physiological, Transcriptomic and Metabolomic Salinity Response Mechanisms inPlants (Basel, Switzerland) · 2023Article
- Effect of gibberellic acid on photosynthesis and oxidative stress response in maize under weak light conditions.Frontiers in plant science · 2023Article
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- Integrative Analysis of Proteomics and Metabolism Reveals the Potential Roles of Arachidonic Acid Metabolism in Hypoxia Response in Mouse Spleen.Molecules (Basel, Switzerland) · 2022Article
- The Ethylene Response Factor ERF5 Regulates Anthocyanin Biosynthesis in 'Zijin' Mulberry Fruits by Interacting withInternational journal of molecular sciences · 2022Article
- The effect ofiScience · 2022Article
- The Antioxidant Properties of Alfalfa (Oxidative medicine and cellular longevity · 2022Article
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- Comprehensive Phosphoproteomic Analysis ofACS omega · 2021Article
- Salinity Stress Alters the Secondary Metabolic Profile ofInternational journal of molecular sciences · 2021Article
Corrections and comments
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Authors and funding
9 authors at 4 institutions in 1 country.
Funding
Abstract
Alfalfa is the most extensively cultivated forage legume worldwide, and salinity constitutes the main environmental scourge limiting its growth and productivity. To unravel the potential molecular mechanism involved in salt tolerance in alfalfa, we accomplished a combined analysis of parallel reaction monitoring-based proteomic technique and targeted metabolism. Based on proteomic analysis, salt stress induced 226 differentially abundant proteins (DAPs). Among them, 118 DAPs related to the antioxidant system, including glutathione metabolism and oxidation-reduction pathways, were significantly up-regulated. Data are available via ProteomeXchange with identifier PXD017166. Overall, 107 determined metabolites revealed that the tricarboxylic acid (TCA) cycle, especially the malate to oxaloacetate conversion step, was strongly stimulated by salt stress. This leads to an up-regulation by about 5 times the ratio of NADPH/NADP
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Registered trials
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