Trial reportNutrients2020
Food Intervention with Folate Reduces TNF-α and Interleukin Levels in Overweight and Obese Women with the
Open access · goldAbstract readRandomized Controlled Trial
In one paragraph
Trial report in Nutrients, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
3.5field-weighted citation impact, top 6% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.
- In the context of the triple burden of malnutrition: A systematic review of gene-diet interactions and nutritional status.Critical reviews in food science and nutrition · 2024Pooled it
- Trial
- Effects of Vitamin B6 and Folic Acid on Cardiometabolic Biomarkers and Cardiac Oxidative Stress in Homocysteine-Loaded Rats.Biomedicines · 2026Article
- Article
- Association between red blood cell folate and accelerated aging in American adults: a cross-sectional study from the national health and nutrition examination survey.Frontiers in nutrition · 2025Article
- Steroids and One-Carbon Metabolism: Clinical Implications in Endocrine Disorders.Neuroendocrinology · 2025Review
- Immunogenetic Aspects of Sarcopenic Obesity.Genes · 2024Review
- Targeting one-carbon metabolism for cancer immunotherapy.Clinical and translational medicine · 2024Review
- Uncovering the Hidden Dangers and Molecular Mechanisms of Excess Folate: A Narrative Review.Nutrients · 2023Review
- TT Genotype ofNutrients · 2023Article
- Maternal pre-pregnancy BMI, MTHFR polymorphisms, and the risk of adverse pregnancy outcomes in pregnant women from South China: a retrospective cohort study.BMC pregnancy and childbirth · 2023Article
- Associations of MTHFR gene polymorphism with lipid metabolism and risk of cerebral infarction in the Northwest Han Chinese population.Frontiers in neurology · 2023Article
- An Exploratory Critical Review on TNF-α as a Potential Inflammatory Biomarker Responsive to Dietary Intervention with Bioactive Foods and Derived Products.Foods (Basel, Switzerland) · 2022Review
- Personalized Nutrition in the Management of Female Infertility: New Insights on Chronic Low-Grade Inflammation.Nutrients · 2022Review
- L-Methylfolate in Antidepressant Non-responders: The Impact of Body Weight and Inflammation.Frontiers in psychiatry · 2022Article
- Multimodal Care for Headaches, Lumbopelvic Pain, and Dysmenorrhea in a Woman With Endometriosis: A Case Report.Journal of chiropractic medicine · 2021Article
- Unmetabolized folic acid is associated with TNF-α, IL-1β and IL-12 concentrations in a population exposed to mandatory food fortification with folic acid: a cross-sectional population-based study in Sao Paulo, Brazil.European journal of nutrition · 2021Article
- Efficacy of metoprolol combined with torasemide in elderly patients with degenerative valvular heart disease and heart failure and its influence on NT-proBNP levels.Pakistan journal of medical sciencesArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
20 authors at 3 institutions in 1 country.
Jéssica Vanessa de Carvalho LisboaPostgraduate Program in Nutrition Sciences, Health Sciences Center, Federal University of Paraíba, João Pessoa 58059-900, Brazil.
Marina Ramalho RibeiroPostgraduate Program in Nutrition Sciences, Health Sciences Center, Federal University of Paraíba, João Pessoa 58059-900, Brazil.
Rafaella Cristhine Pordeus LunaPostgraduate Program in Nutrition Sciences, Health Sciences Center, Federal University of Paraíba, João Pessoa 58059-900, Brazil.
Raquel Patrícia Ataíde LimaPostgraduate Program in Nutrition Sciences, Health Sciences Center, Federal University of Paraíba, João Pessoa 58059-900, Brazil.
Rayner Anderson Ferreira do NascimentoPostgraduate Program in Molecular and Human Biology, Center of Exact and Natural Sciences, Federal University of Paraíba, João Pessoa 58059-900, Brazil.
Mussara Gomes Cavalcante Alves MonteiroPostgraduate Program in Nutrition Sciences, Health Sciences Center, Federal University of Paraíba, João Pessoa 58059-900, Brazil.
Keylha Querino de Farias LimaPostgraduate Program in Nutrition Sciences, Health Sciences Center, Federal University of Paraíba, João Pessoa 58059-900, Brazil.
Carla Patrícia Novaes Dos Santos FechinePostgraduate Program in Nutrition Sciences, Health Sciences Center, Federal University of Paraíba, João Pessoa 58059-900, Brazil.
Naila Francis Paulo de OliveiraDepartament of Molecular Biology, Federal University of Paraíba, João Pessoa 58059-900, Brazil.
Darlene Camati PersuhnPostgraduate Program in Nutrition Sciences, Health Sciences Center, Federal University of Paraíba, João Pessoa 58059-900, Brazil.
Robson Cavalcante VerasPostgraduate Program in Nutrition Sciences, Health Sciences Center, Federal University of Paraíba, João Pessoa 58059-900, Brazil.
Maria da Conceição Rodrigues GonçalvesPostgraduate Program in Nutrition Sciences, Health Sciences Center, Federal University of Paraíba, João Pessoa 58059-900, Brazil.
Flávia Emília Leite de Lima FerreiraPostgraduate Program in Nutrition Sciences, Health Sciences Center, Federal University of Paraíba, João Pessoa 58059-900, Brazil.
Roberto Teixeira LimaPostgraduate Program in Nutrition Sciences, Health Sciences Center, Federal University of Paraíba, João Pessoa 58059-900, Brazil.
Alexandre Sérgio da SilvaPostgraduate Program in Nutrition Sciences, Health Sciences Center, Federal University of Paraíba, João Pessoa 58059-900, Brazil.
Alcides da Silva DinizPostgraduate Program in Nutrition Sciences, Federal University of Pernambuco, Recife 50670901, Brazil.
Aléssio Tony Cavalcanti de AlmeidaDepartment of Economics, Postgraduate Program in App1lied Economics and Economics of the Public Sector, Center for Applied Social Sciences, Federal University of Paraíba, João Pessoa 58059-900, Brazil.
Ronei Marcos de MoraesPostgraduate Program in Health Decision Models, Federal University of Paraíba, João Pessoa 58059-900, Brazil.
Eliseu Verly JuniorDepartment of Epidemiology, Institute of Social Medicine, State University of Rio de Janeiro, Rio de Janeiro 20550-900, Brazil.
Maria José de Carvalho CostaPostgraduate Program in Nutrition Sciences, Health Sciences Center, Federal University of Paraíba, João Pessoa 58059-900, Brazil.
Universidade Federal da Paraíba · BRUniversidade do Estado do Rio de Janeiro · BRUniversidade Federal de Pernambuco · BR
Funding
Foundation for Support and Research Support/PPSUS/PB/Ministry of Health/National Research Council/CNPq/João Pessoa Prefecture public notice 001/2013 under the number EFP_00008187
Abstract
Methylenetetrahydrofolate reductase (
Indexed as
VegetablesAdultDietDiet SurveysDouble-Blind MethodFemaleFolic AcidGenotypeHomocysteineHumansInterleukin-1betaInterleukin-6Methylenetetrahydrofolate Reductase (NADPH2)Middle AgedNutrigenomicsObesityFolic AcidHomocysteineIL6 protein, humanInterleukin-1betaInterleukin-6Methylenetetrahydrofolate Reductase (NADPH2)MTHFR protein, humanTumor Necrosis Factor-alphaVitamin B 12dietary interventionfolategenetic variantsinterleukinsobesityoverweightpolymorphismtumor necrosis factor-alpha
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.