Evidence map›Paper›PMID 32019121›Full record

ArticleMedicina (Kaunas, Lithuania)2020

Overexpression of KLF17 Predicts a Favorable Prognosis in Patients with Oral Squamous Cell Carcinoma: A Retrospective Study.

Yi-Ju Lee, Lung Chan, Chung-Min Yeh, Chien-Hsun Lee, Wen-Wei Sung

Open access · goldAbstract read
In one paragraph

Article in Medicina (Kaunas, Lithuania), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. KLF7: a new candidate biomarker and therapeutic target for high-grade serous ovarian cancer.Journal of experimental & clinical cancer research : CR · 2020
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Yi-Ju LeeDepartment of Pathology, Chung Shan Medical University, Taichung 40201, Taiwan.
Lung ChanSchool of Medicine, Chung Shan Medical University, Taichung 40201, Taiwan.
Chung-Min YehDepartment of Pathology, Changhua Christian Hospital, Changhua 50006, Taiwan.
Chien-Hsun LeeDepartment of Pathology, Changhua Christian Hospital, Changhua 50006, Taiwan.
Wen-Wei SungSchool of Medicine, Chung Shan Medical University, Taichung 40201, Taiwan.
Chung Shan Medical University Hospital · TWChanghua Christian Hospital · TWChung Shan Medical University · TWKang-Ning Junior College of Medical Care and Management · TW

Funding

Chung Shan Medical University Hospital CSH-2017-C-036
6 · The paper itself

Abstract

BACKGROUND AND

objectivesPatients with oral squamous cell carcinoma (OSCC), a common malignancy in Asian countries, have a poor prognosis. We investigated the role of Krüppel-like factor 17 (KLF17) and its prognostic significance in OSCC. MATERIALS AND

methodsKLF17 expression was measured by immunohistochemical staining of specimens from 283 patients with OSCC. We analyzed correlations between KLF17 expression and clinicopathologic features and between KLF17 expression and overall survival. The prognostic value of KLF17 was tested using Kaplan-Meier analysis and Cox proportional hazard models.

resultsAmong the 283 patients, high KLF17 expression was significantly associated with an early OSCC stage and low

conclusionsHigh KLF17 expression can serve as a marker for a favorable prognosis in patients with OSCC. The prognostic role of KLF17 is more significant in patients with a history of betel quid chewing or a low

Indexed as

Carcinoma, Squamous CellConfidence IntervalsFemaleHumansImmunohistochemistryKaplan-Meier EstimateMaleMiddle AgedMouth NeoplasmsNeoplasm ProteinsPrognosisProportional Hazards ModelsRetrospective StudiesSurvival RateTranscription FactorsKLF17 protein, humanNeoplasm ProteinsTranscription FactorsKLF17Krüppel-like factor 17oral canceroral squamous cell carcinomaoverall survivalprognosis

Identifiers

PMID32019121
PMCPMC7073896
OpenAlexW3003501817

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.