Evidence map›Paper›PMID 32019101›Full record

ArticlePharmaceutics2020

Selective Laser Sintering 3D Printing of Orally Disintegrating Printlets Containing Ondansetron.

Nour Allahham, Fabrizio Fina, Carmen Marcuta, Lilia Kraschew, Wolfgang Mohr, Simon Gaisford, Abdul W Basit, Alvaro Goyanes

Open access · goldAbstract read
In one paragraph

Article in Pharmaceutics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed
10.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 187 citations in OpenAlex.

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  15. 3D-printed dosage forms for oral administration: a review.Drug delivery and translational research · 2024
    Review
  16. Formulating biopharmaceuticals using three-dimensional printing.Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques · 2024
    Review
  17. Article
  18. A case study on decentralized manufacturing of 3D printed medicines.International journal of pharmaceutics: X · 2023
    Article
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  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Nour AllahhamFabRx Ltd., 3 Romney Road, Ashford, Kent TN24 0RW, UK.
Fabrizio FinaDepartment of Pharmaceutics, UCL School of Pharmacy, University College London, 29-39 Brunswick Square, London WC1N 1AX, UK.
Carmen MarcutaLosan Pharma GmbH, Otto-Hahn-Strasse 13, 79395 Neuenburg, Germany.
Lilia KraschewLosan Pharma GmbH, Otto-Hahn-Strasse 13, 79395 Neuenburg, Germany.
Wolfgang MohrLosan Pharma GmbH, Otto-Hahn-Strasse 13, 79395 Neuenburg, Germany.
Simon GaisfordFabRx Ltd., 3 Romney Road, Ashford, Kent TN24 0RW, UK.
Abdul W BasitFabRx Ltd., 3 Romney Road, Ashford, Kent TN24 0RW, UK.
Alvaro GoyanesFabRx Ltd., 3 Romney Road, Ashford, Kent TN24 0RW, UK.
University College London · GBUniversidade de Santiago de Compostela · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this work was to explore the feasibility of using selective laser sintering (SLS) 3D printing (3DP) to fabricate orodispersable printlets (ODPs) containing ondansetron. Ondansetron was first incorporated into drug-cyclodextrin complexes and then combined with the filler mannitol. Two 3D printed formulations with different levels of mannitol were prepared and tested, and a commercial ondansetron orally disintegrating tablet (ODT) product (Vonau

Indexed as

3D printed drug productsadditive manufacturingorally disintegrating printlets (ODPs)orally disintegrating tablets (ODTs)personalized medicinesprinting pharmaceuticalsrapid prototypingtaste maskingthree-dimensional printing

Identifiers

PMID32019101
PMCPMC7076455
OpenAlexW3003342647

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.