Evidence map›Paper›PMID 32018280›Full record

ArticleEuropean journal of dentistry2020

Comparative Fluoride Release and Antimicrobial Analysis of Commercial and Experimental Bioactive Glass/Nano-Oxide-Based Dentifrices.

Hashmat Gul, Maleeha Nayyer, Mehreen Gilani, Nadia Aman, Azad Ali Azad, Asma Tufail Shah, Aqif Anwar Chaudhry, Muhammad Kaleem, Abdul Samad Khan

Open access · hybridAbstract read
In one paragraph

Article in European journal of dentistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Hashmat GulDepartment of Dental Materials, Army Medical College, National University of Medical Sciences, Rawalpindi, Pakistan.
Maleeha NayyerDepartment of Dental Materials, Army Medical College, National University of Medical Sciences, Rawalpindi, Pakistan.
Mehreen GilaniDepartment of Microbiology, Army Medical College, National University of Medical Sciences, Rawalpindi, Pakistan.
Nadia AmanDepartment of Operative Dentistry, Foundation University Medical College, Islamabad, Pakistan.
Azad Ali AzadDepartment of Prosthodontics, Armed Forces Institute of Dentistry, National University of Medical Sciences, Rawalpindi, Pakistan.
Asma Tufail ShahInterdisciplinary Research Center in Biomedical Materials, COMSATS University Islamabad Lahore Campus, Lahore, Pakistan.
Aqif Anwar ChaudhryInterdisciplinary Research Center in Biomedical Materials, COMSATS University Islamabad Lahore Campus, Lahore, Pakistan.
Muhammad KaleemDepartment of Dental Materials, Army Medical College, National University of Medical Sciences, Rawalpindi, Pakistan.
Abdul Samad KhanDepartment of Restorative Dental Sciences, College of Dentistry, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia.ORCID 0000-0002-2165-800X
National University of Medical Sciences · PKCOMSATS University Islamabad · PKFoundation University Medical College · PKImam Abdulrahman Bin Faisal University · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe objectives were to measure fluoride release and assess the antimicrobial behavior of fluoride-doped nano bioactive glass (F-nBG) and nano zinc oxide (ZnO)-enriched novel dentifrices. MATERIALS AND

methodsExperimental dentifrices were synthesized by incorporating ZnO nanoparticles and F-nBG (1.5 wt% and 4 wt%) as active ingredients. The fluoride release behavior of suspensions and elutes of samples were analyzed by ion selective electrode. Antimicrobial activity and minimum bactericidal concentration against

resultsThe fluoride release behavior of experimental dentifrices was higher than that of commercial dentifrices and was dependent on filler loading. The fluoride release was more from suspensions than elutes. Zones of inhibition (ZOIs) and minimum bactericidal concentration values for novel dentifrices showed direct proportionality with filler loading, and effectiveness was exhibited against both strains. Experimental dentifrices exhibited effective antibacterial potential, which could possibly be due to release of sufficient fluoride and zinc ions in aqueous media from F-nBG and ZnO present in their formulations.

conclusionCombination of F-nBG and ZnO may provide a multi-benefit approach for simultaneously treating early white spot lesions, reducing bacterial growth, and providing core plaque control.

Identifiers

PMID32018280
PMCPMC7069735
OpenAlexW3005238823

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.