Evidence map›Paper›PMID 32018219›Full record

ArticleBiomedicine & pharmacotherapy = Biomedecine & pharmacotherapie2020

Comparison of the pharmacologic profiles of arginine vasopressin and oxytocin analogs at marmoset, titi monkey, macaque, and human oxytocin receptors.

Marsha L Pierce, Jeffrey A French, Thomas F Murray

Open access · goldAbstract read
In one paragraph

Article in Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

  1. Article
  2. The neural circuits of monogamous behavior.Frontiers in neural circuits · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Marsha L PierceDepartment of Pharmacology, Creighton University School of Medicine, 2500 California Plaza, Omaha, NE, 68178, USA; Department of Pharmacology, Midwestern University, 555 31St., Downers Grove, IL, 60515, USA. Electronic address: MarshaPierce@creighton.edu.
Jeffrey A FrenchDepartment of Psychology, University of Nebraska Omaha, 6001 Dodge St., Omaha, NE, 68182, USA. Electronic address: jfrench@unomaha.edu.
Thomas F MurrayDepartment of Pharmacology, Creighton University School of Medicine, 2500 California Plaza, Omaha, NE, 68178, USA. Electronic address: tfmurray@creighton.edu.
Creighton University · USMidwestern University · USUniversity of Nebraska at Omaha · US

Funding

Oxytocin Ligand/Receptor Variants and Social BehaviorR01HD089147 · NICHD · UNIVERSITY OF NEBRASKA OMAHA · PI FRENCH, JEFFREY A · 2016 to 2020
$1.5M
NICHD NIH HHS R01 HD089147
6 · The paper itself

Abstract

The oxytocin-arginine vasopressin (OT-AVP) ligand-receptor family influences a variety of physiological, behavioral, and social behavioral processes in the brain and periphery. The OT-AVP family is highly conserved in mammals, but recent discoveries have revealed remarkable diversity in OT ligands and receptors in New World Monkeys (NWMs) providing a unique opportunity to assess the effects of genetic variation on pharmacological signatures of peptide ligands. The consensus mammalian OT sequence has leucine in the 8

Indexed as

AnimalsArginine VasopressinCalciumCallicebusCallithrixCHO CellsCricetinaeCricetulusHumansMacacaMembrane PotentialsOxytocinPertussis ToxinReceptors, VasopressinThapsigarginArginine VasopressinCalciumOxytocinPertussis ToxinReceptors, VasopressinThapsigarginArginine vasopressinCalcium-activated potassium channelG-protein coupled receptorOxytocinOxytocin receptor

Identifiers

PMID32018219
PMCPMC7196279
OpenAlexW3003233116

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.