Evidence map›Paper›PMID 32017439›Full record

ArticleJournal of diabetes investigation2020

Vitamin D levels, prediabetes risk and hemoglobin A1c levels in young non-diabetic Saudi women.

Maha A Al-Mohaissen, Terry Lee, Ali Faris Alamri

Open access · goldAbstract read
In one paragraph

Article in Journal of diabetes investigation, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Maha A Al-MohaissenDepartment of Clinical Sciences, Cardiology, Princess Nourah Bint Abdulrahman University, Riyadh, Saudi Arabia.ORCID https://orcid.org/0000-0002-5145-0648
Terry LeeCenter for Health Evaluation and Outcome Sciences, Vancouver, British Columbia, Canada.
Ali Faris AlamriDepartment of Family Medicine, King Abdullah bin Abdulaziz University Hospital, Princess Nourah bint Abdulrahman University, Riyadh, Saudi Arabia.
Princess Nourah bint Abdulrahman University · SACentre for Advancing Health Outcomes · CA

Funding

The Cardiovascular Disease in Women Research Chair at Princess Nourah bint Abdulrahman University. CDW-2019-03
6 · The paper itself

Abstract

AIMS/

introductionVitamin D levels are negatively correlated with prediabetes risk and hemoglobin A1c levels in individuals with prediabetes. The data are, however, scarce and inconsistent among different populations. We aimed to assess the association of vitamin D with prediabetes risk and hemoglobin A1c levels in young Saudi women with normoglycemia and prediabetes. MATERIALS AND

methodsWe analyzed the data of individuals without diabetes (without diabetes history and hemoglobin A1c <6.4%) from the Princess Nourah bint Abdulrahman University's non-communicable diseases student registry. Demographic data, anthropometric and blood pressure measurements, and hemoglobin A1c and vitamin D results were retrieved and analyzed.

resultsIn total, 345 participants were included in the analysis. The prediabetes status showed no association with vitamin D levels, but it was significantly associated with the participants' weight and body mass index. Additionally, there was no correlation between the levels of vitamin D and hemoglobin A1c across the whole population, even after correction for body mass index. However, in the body mass index subgroups, when individuals with potentially harmful levels of vitamin D (>125 nmol/L) were excluded, a positive association was detected between vitamin D and hemoglobin A1c levels in the underweight individuals. Hemoglobin A1c values showed a positive correlation only with bodyweight and body mass index.

conclusionsVitamin D levels did not predict prediabetes status and showed no correlation with hemoglobin A1c levels in this population. Vitamin D levels' effect on the risk of prediabetes might be small compared with other well-established risk factors, such as obesity.

Indexed as

AdolescentAdultBiomarkersBlood GlucoseBody Mass IndexCase-Control StudiesDiabetes Mellitus, Type 2FemaleFollow-Up StudiesGlycated HemoglobinHumansPrediabetic StatePrognosisRisk FactorsSaudi ArabiaVitamin DBiomarkersBlood GlucoseGlycated Hemoglobinhemoglobin A1c protein, humanVitamin DVitaminsHemoglobin A1cPrediabetesVitamin D

Identifiers

PMID32017439
PMCPMC7477525
OpenAlexW3005515292

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.