Evidence map›Paper›PMID 32017181›Full record

ArticleJournal of cardiac surgery2020

The effect of catheter-directed thrombolytic use on readmission rates and in-hospital outcomes among cancer patients with venous thromboembolism in the United States.

Avirup Guha, Grant McKinley, Amit K Dey, Rebecca Carter, P Elliott Miller, Abhishek J Deshmukh, Raja Zaghlol, Ana Barac, Nihar R Desai, Daniel Addison

Open access · greenAbstract read
In one paragraph

Article in Journal of cardiac surgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.1field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 7 institutions in 2 countries.

Avirup GuhaCardio-Oncology Program, Division of Cardiology, The Ohio State University, Columbus, Ohio.ORCID http://orcid.org/0000-0003-0253-1174
Grant McKinleyCardio-Oncology Program, Division of Cardiology, The Ohio State University, Columbus, Ohio.
Amit K DeyDivision of Cardiology, National Heart Lung and Blood Institute, Bethesda, Maryland.
Rebecca CarterCardio-Oncology Program, Division of Cardiology, The Ohio State University, Columbus, Ohio.
P Elliott MillerDivision of Cardiology, Yale University School of Medicine, New Haven, Connecticut.
Abhishek J DeshmukhDivision of Cardiology, Mayo Clinic, Rochester, Minnesota.
Raja ZaghlolDivision of Cardiology, Washington Hospital Center, Washington, District of Columbia.
Ana BaracDivision of Cardiology, Washington Hospital Center, Washington, District of Columbia.
Nihar R DesaiDivision of Cardiology, Yale University School of Medicine, New Haven, Connecticut.
Daniel AddisonCardio-Oncology Program, Division of Cardiology, The Ohio State University, Columbus, Ohio.
MedStar Washington Hospital Center · USYale University · USZero to Three · USMayo Clinic · USNational Heart Lung and Blood Institute · USThe Ohio State University · USThe Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Translational Training Grant in Experimental TherapeuticsK12CA133250 · NCI · OHIO STATE UNIVERSITY · PI WILLIAM E. CARSON, Rosa Lapalombella · 2008 to 2026
$15.0M
NCATS NIH HHS UL1 TR001863NCI NIH HHS K12 CA133250NCI NIH HHS K12CA133250
6 · The paper itself

Abstract

backgroundCancer inducing a hypercoagulable state, venous thromboembolism (VTE) remains a leading cause of morbidity and mortality globally. We assessed the impacts of cancer on the likelihood for readmission after a VTE-targeted procedure.

methodsWe created a new cohort using discharge-level data from all hospitalizations from State Inpatient Databases of geographically dispersed participating states (18-27 states).

resultsIn those presenting with VTE during index-admission (619 241), 2.4% patients underwent catheter directed thrombolytic therapy (CDL) on index admission and among those 20.3% had cancer. Moreover, the 30-day readmission rate amongst CDL recipients (10 776 overall) was 14.3% in those with cancer compared to 8.8% in those with no cancer history (P < .0001). Additionally, in-hospital mortality (5.7% vs 1.1%; P = 0.009) and cost-of-care ($11 014 ± 914 vs $10 520 ± 534; P = .04) was significantly higher in cancer compared to noncancer.

conclusionThe use of CDL does not appear to reduce the risk of returning for a VTE-related admission in cancer.

Indexed as

Hospital MortalityCathetersCohort StudiesCosts and Cost AnalysisFemaleHumansMaleMechanical ThrombolysisMiddle AgedNeoplasmsPatient ReadmissionUnited StatesVenous Thromboembolismcancercatheter directed thrombolyticcost of carereadmissionvenous thromboembolism

Identifiers

PMID32017181
PMCPMC7860638
OpenAlexW3004252467

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.