ArticleInternational urology and nephrology2020
Serum albumin changes and mortality risk of peritoneal dialysis patients.
Article in International urology and nephrology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Pooled it
- Using interpretable machine learning to analyze the trajectory changes of serum albumin to predict the mortality rate of sepsis: a cohort study based on MIMIC-IV.BMC infectious diseases · 2026Article
- Impact of albumin variability during the first year on prognosis in peritoneal dialysis patients.Scientific reports · 2026Article
- A retrospective cohort study on the association between RAR and mortality in peritoneal Dialysis patients.BMC nephrology · 2026Article
- Dynamic mortality predictions from serum albumin in dialysis patients using robust joint models with competing risks.Scientific reports · 2025Article
- Dietary energy intake predicts mortality in Chinese patients with peritoneal dialysis: a single-center 18 years' follow-up study.BMC nephrology · 2025Article
- Assessing biomarker trajectories for mortality risk in peritoneal dialysis: A focus on multivariate joint modeling.PloS one · 2025Article
- Epidemiology, drug resistance, and clinical risk factors of peritoneal dialysis-associated peritonitis: a five-year multicenter study.Frontiers in cellular and infection microbiology · 2025Article
- The neutrophil percentage-to-albumin ratio is an independent risk factor for poor prognosis in peritoneal dialysis patients.Renal failure · 2024Article
- Omicron variant infection worsen the prognosis of haemodialysis (HD) patients.Annals of medicine · 2024Article
- Comparison of mortality according to baseline, first year, and mean albumin levels in peritoneal dialysis: a retrospective study.Renal failure · 2023Article
- Associations between liver function parameters and poor clinical outcomes in peritoneal dialysis patients.Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy · 2023Review
- Use of the systemic inflammation response index (SIRI) as a novel prognostic marker for patients on peritoneal dialysis.Renal failure · 2022Article
- Risk Factors and Pathogen Spectrum in Continuous Ambulatory Peritoneal Dialysis-Associated Peritonitis: A Single Center Retrospective Study.Medical science monitor : international medical journal of experimental and clinical research · 2022Article
- Dynamic serum albumin and outcome of peritoneal dialysis patients: A retrospective study in China.Frontiers in medicine · 2022Article
- Effect of Serum Albumin Changes on Mortality in Patients with Peritoneal Dialysis: A Joint Modeling Approach and Personalized Dynamic Risk Predictions.BioMed research international · 2021Article
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4 authors.
Funding
Abstract
purposeInitial or single time point serum albumin levels have been shown to be important in predicting the prognosis of peritoneal dialysis (PD) patients. However, we assume the dynamic change and trend of albumin after PD are essential. We aimed to investigate the association between baseline albumin levels, albumin trajectories, and patient mortality in a retrospective cohort study.
methodsIn this retrospective cohort study, 547 incident PD patients were enrolled from Peking University Third Hospital. Date were collected by medical records review, including age, gender, body mass index, primary disease, comorbidities, and laboratory tests. A joint model for longitudinal data and time-to-event data was used to establish the relationship between serum albumin trajectories and mortality risk of PD patients.
resultsThe albumin trajectories was negatively correlated with risk of death. The increase in the current value of albumin trajectories at time points t after PD was associated with decreased risk of death (HR = 0.881, p < 0.0001). There was no statistical association between initial albumin and risk of death (HR = 1.030, 95% CI 0. 995-1.066). The results showed that increased age, higher albumin-corrected Ca levels, and higher eGFR values were risk factors for death. In addition, predictors of low albumin levels are increased PD time, increased age, increased albumin-corrected Ca, and decreased BMI as well as initial albumin levels.
conclusionThis study demonstrates that albumin trajectories after PD is better than initial serum albumin level in predicting mortality risk. Increasing albumin level over time can improve the prognosis of PD patients.
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