Evidence map›Paper›PMID 32016857›Full record

ArticlePharmacological reports : PR2020

α

Thiago Roberto Lima Romero, Marina Gomes Miranda E Castor, Cosimo Parrella, Fabiana Piscitelli, Vincenzo Di Marzo, Igor Dimitri Gama Duarte

Abstract read
PubMed Publisher
In one paragraph

Article in Pharmacological reports : PR, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Thiago Roberto Lima RomeroDepartment of Pharmacology, Institute of Biological Sciences, ICB-UFMG, Av. Antônio Carlos, 6627, Pampulha, Belo Horizonte, MG, CEP 31.270-100, Brazil. thiromero@gmail.com.
Marina Gomes Miranda E CastorDepartment of Pharmacology, Institute of Biological Sciences, ICB-UFMG, Av. Antônio Carlos, 6627, Pampulha, Belo Horizonte, MG, CEP 31.270-100, Brazil.
Cosimo ParrellaEndocannabinoid Research Group, Institute of Biomolecular Chemistry, National Research Council, via Campi Flegrei, 34, Comprensorio Olivetti, 80078, Pozzuoli, NA, Italy.
Fabiana PiscitelliEndocannabinoid Research Group, Institute of Biomolecular Chemistry, National Research Council, via Campi Flegrei, 34, Comprensorio Olivetti, 80078, Pozzuoli, NA, Italy.
Vincenzo Di MarzoEndocannabinoid Research Group, Institute of Biomolecular Chemistry, National Research Council, via Campi Flegrei, 34, Comprensorio Olivetti, 80078, Pozzuoli, NA, Italy.
Igor Dimitri Gama DuarteDepartment of Pharmacology, Institute of Biological Sciences, ICB-UFMG, Av. Antônio Carlos, 6627, Pampulha, Belo Horizonte, MG, CEP 31.270-100, Brazil.
National Research Council · ITUniversidade Federal de Minas Gerais · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundXylazine is an α

methodsThe rat paw pressure test, in which hyperalgesia was induced by the intraplantar injection of prostaglandin E

resultsXylazine administered via an intraplantar injection (25, 50 and 100 μg) induced a peripheral antinociceptive effect against prostaglandin E

conclusionsThe present results provides evidence that the peripheral antinociceptive effect of the α

Indexed as

Adrenergic alpha-2 Receptor AgonistsAnalgesicsAnimalsArachidonic AcidsChromatography, LiquidDisease Models, AnimalDose-Response Relationship, DrugEndocannabinoidsHyperalgesiaMaleMass SpectrometryPolyunsaturated AlkamidesRatsRats, WistarReceptor, Cannabinoid, CB1XylazineAdrenergic alpha-2 Receptor AgonistsAnalgesicsanandamideArachidonic AcidsEndocannabinoidsPolyunsaturated AlkamidesReceptor, Cannabinoid, CB1XylazineAnandamideCB1 cannabinoidPeripheral antinociceptionXylazineα2-Adrenoceptor

Identifiers

PMID32016857
OpenAlexW3000620877

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.