Evidence map›Paper›PMID 32016793›Full record

ArticleNeurochemical research2020

Neuroprotective Effects of Deuterium-Depleted Water (DDW) Against H

Yongfu Wu, Dongyun Qin, Huiling Yang, Wenya Wang, Jifei Xiao, Le Zhou, Hui Fu

Abstract read
PubMed Publisher
In one paragraph

Article in Neurochemical research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.3field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 26 citations in OpenAlex.

  1. Review
  2. Article
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  7. Review
  8. Review
  9. Neuroprotective Effect ofBioengineering (Basel, Switzerland) · 2022
    Article
  10. Article
  11. Article
  12. Effects of Heavy Isotopes (Sports (Basel, Switzerland) · 2021
    Article
  13. Novel neuroprotective peptides in the venom of the solitary scoliid waspThe journal of venomous animals and toxins including tropical diseases · 2021
    Article
  14. Article
  15. Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Yongfu WuGuangdong Key Laboratory for Research and Development of Natural Drugs, School of Pharmacy, Guangdong Medical University, No. 1, Xincheng Road of Songshan Lake Science and Technology Industry Park, Dongguan, 523808, Guangdong, China.
Dongyun QinGuangdong Key Laboratory for Research and Development of Natural Drugs, School of Pharmacy, Guangdong Medical University, No. 1, Xincheng Road of Songshan Lake Science and Technology Industry Park, Dongguan, 523808, Guangdong, China.
Huiling YangGuangdong Key Laboratory for Research and Development of Natural Drugs, School of Pharmacy, Guangdong Medical University, No. 1, Xincheng Road of Songshan Lake Science and Technology Industry Park, Dongguan, 523808, Guangdong, China.
Wenya WangSchool of Pharmaceutical Sciences, Southern Medical University, Guangzhou, 510515, China.
Jifei XiaoInternational Department, The Affiliated High School of South China Normal University, Guangzhou, 510631, China.
Le ZhouGuangdong Key Laboratory for Research and Development of Natural Drugs, School of Pharmacy, Guangdong Medical University, No. 1, Xincheng Road of Songshan Lake Science and Technology Industry Park, Dongguan, 523808, Guangdong, China.
Hui FuGuangdong Key Laboratory for Research and Development of Natural Drugs, School of Pharmacy, Guangdong Medical University, No. 1, Xincheng Road of Songshan Lake Science and Technology Industry Park, Dongguan, 523808, Guangdong, China. zoefu2014@126.com.
Guangdong Medical College · CNSouth China Normal University · CNSouthern Medical University · CN

Funding

Construct TCM Research Program of Guangdong 20162080Scientific Research Fund of Guangdong Medical University 2018007
6 · The paper itself

Abstract

Oxidative stress plays an important role in the pathogenesis of neurodegenerative diseases, including Alzheimer's disease and Parkinson's disease. Induction of endogenous antioxidants to act against oxidative stress-mediated neuronal damage seems to be a reasonable strategy for delaying the progression of such diseases. In this study, we investigated the neuroprotective effect of deuterium-depleted water (DDW) against H

Indexed as

AnimalsCell SurvivalDeuteriumDose-Response Relationship, DrugHydrogen PeroxideNeuroprotective AgentsOxidative StressPC12 CellsPhosphatidylinositol 3-KinasePhosphoinositide-3 Kinase InhibitorsProto-Oncogene Proteins c-aktRatsSignal TransductionWaterDeuteriumHydrogen PeroxideNeuroprotective AgentsPhosphatidylinositol 3-KinasePhosphoinositide-3 Kinase InhibitorsProto-Oncogene Proteins c-aktWaterDeuterium-depleted water (DDW)Neuroprotective effectOxidative stressPC12 cells

Identifiers

PMID32016793
OpenAlexW3003403795

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.