Evidence map›Paper›PMID 32016773›Full record

ArticleJournal of physiology and biochemistry2020

Deficiency of T-type voltage-gated calcium channels results in attenuated weight gain and improved endothelium-dependent dilatation of resistance vessels induced by a high-fat diet in mice.

Kristoffer Rosenstand, Kenneth Andersen, Rasmus Terp, Peter Gennemark, Ditte Gry Ellman, Anna Reznichenko, Kate Lykke Lambertsen, Paul M Vanhoutte, Pernille B L Hansen, Per Svenningsen

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of physiology and biochemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. [Mibefradil improves skeletal muscle mass, function and structure in obese mice].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2022
    Article
  3. Article
  4. Review
  5. Adipocyte-Endothelium Crosstalk in Obesity.Frontiers in endocrinology · 2021
    Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 3 countries.

Kristoffer RosenstandInstitute of Molecular Medicine, Department of Cardiovascular and Renal Research, University of Southern Denmark, Odense, Denmark.
Kenneth AndersenInstitute of Molecular Medicine, Department of Cardiovascular and Renal Research, University of Southern Denmark, Odense, Denmark.
Rasmus TerpInstitute of Molecular Medicine, Department of Cardiovascular and Renal Research, University of Southern Denmark, Odense, Denmark.
Peter GennemarkResearch and Early Development, Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.
Ditte Gry EllmanDepartment of Neurobiology Research, Institute of Molecular Medicine, University of Southern Denmark, Odense, Denmark.
Anna ReznichenkoResearch and Early Development, Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.
Kate Lykke LambertsenDepartment of Neurobiology Research, Institute of Molecular Medicine, University of Southern Denmark, Odense, Denmark.
Paul M VanhoutteState Key Laboratory for Pharmaceutical Biotechnology and Department of Pharmacology and Pharmacy, Li Ka Shing Faculty of Medicine, University of Hong Kong, Pok Fu Lam, Hong Kong, China.
Pernille B L HansenInstitute of Molecular Medicine, Department of Cardiovascular and Renal Research, University of Southern Denmark, Odense, Denmark.
Per SvenningsenInstitute of Molecular Medicine, Department of Cardiovascular and Renal Research, University of Southern Denmark, Odense, Denmark. psvenningsen@health.sdu.dk.ORCID http://orcid.org/0000-0001-6590-7103
University of Southern Denmark · DKAstraZeneca (Sweden) · SEUniversity of Hong Kong · HK

Funding

Hjerteforeningen 11-04-R84-A3492-22663Novo Nordisk Fonden 13273Sundhed og Sygdom, Det Frie Forskningsråd 11-107552
6 · The paper itself

Abstract

The deletion of T-type Ca

Indexed as

AnimalsAorta, ThoracicCalciumCalcium Channels, T-TypeCholesterolDiet, High-FatDilatation, PathologicFemaleMaleMesenteric ArteriesMiceMice, Inbred C57BLNitric OxideObesityVascular ResistanceWeight GainCalciumCalcium Channels, T-TypeCholesterolNitric OxideCalciumEndotheliumIon channelsObesity

Identifiers

PMID32016773
OpenAlexW3005095181

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.