ArticleQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2020
Health-related quality of life in Egyptian children with nephrotic syndrome.
Article in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Reliability of generic quality-of-life instruments in assessing health-related quality of life among children and adolescents with idiopathic nephrotic syndrome: a systematic review.Health and quality of life outcomes · 2021Pooled it
- Health-related quality of life of children with first onset steroid-sensitive nephrotic syndrome.European journal of pediatrics · 2023Trial
- Prevalence of corticosteroid-induced cataracts in children with nephrotic syndrome: a cross-sectional study in Pakistan.Childhood kidney diseases · 2026Article
- Generic health-related quality of life instruments among children and adolescents in low- and middle-income countries: a scoping review.Systematic reviews · 2026Article
- Subclinical systolic dysfunction in children with steroid-resistant nephrotic syndrome identified by speckle tracking echocardiography.BMC pediatrics · 2025Article
- Health-Related Quality of Life in Children with Steroid-Resistant Nephrotic Syndrome.Sultan Qaboos University medical journal · 2025Article
- Serum Vitamin D in Children with Hemophilia A and Its Association with Joint Health and Quality of Life.Hematology reports · 2024Article
- Assessment of health-related quality of life of children with idiopathic nephrotic syndrome and their caregivers in China.Health and quality of life outcomes · 2024Article
- Mental health and professional outcomes in parents of children with chronic kidney disease.Pediatric nephrology (Berlin, Germany) · 2024Article
- Health-Related Quality of Life in Sudanese Children with Nephrotic Syndrome: A Comparative Cross-Sectional Study.Pediatric health, medicine and therapeutics · 2024Article
- Health Related Quality of Life in Juvenile-Onset Systemic Lupus Erythematosus: A Questionnaire-Based Study.Maternal and child health journal · 2023Article
- Illness-related parental stress and quality of life in children with kidney diseases.Pediatric nephrology (Berlin, Germany) · 2023Article
- Quality of life in children with nephrotic syndrome: a cross-sectional study using Hindi version of PedsQL 4.0 Generic Core Scales.Clinical and experimental nephrology · 2022Article
- Assessment of health-related quality of life in Sudanese children with nephrotic syndrome: a questionnaire-based study.The Pan African medical journal · 2022Article
- Vascular Endothelial Growth Factor (VEGF) and Neopterin Levels in Children with Steroid-sensitive and Steroid-resistant Nephrotic Syndrome.Medical archives (Sarajevo, Bosnia and Herzegovina) · 2021Article
- Quality of Life of Children with Idiopathic Nephrotic Syndrome.Indian journal of nephrologyArticle
- Design of a User-Centered Electronic Health Tool for Glomerular Disease Management.Glomerular diseasesArticle
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThis research aimed to evaluate Quality of life (QoL) in Egyptian children with idiopathic Nephrotic syndrome (INS) in comparison to healthy children and children with chronic non-renal illnesses.
methodsIn this questionnaire-based study, 300 children were included, 100 with INS and 2 matched control groups: healthy group, and chronic non-renal illness group. QoL was assessed using the Pediatric Quality of Life Inventory (PedsQL™ 4.0 Generic Core Scales) and the Generic Children's QoL Measure (GCQ).
resultsAll mean scores of PedsQL domains in INS group were significantly higher than chronic non-renal illness group and significantly lower than the healthy control group (p = < 0.001) for all and similar results reported also regarding GCQ scores in INS compared to diseased (p = 0.02) and healthy controls (p = 0.006). Steroid-resistant NS group had lowest scores in all domains (p = < 0.001) compared to other clinical phenotypes of NS group. The long duration of illness, higher number of relapses, high cumulative steroid dose, and high number of medications used were associated with lower PedsQL and GCQ scores (p < 0.001 for all)
conclusionThis is the first study to asses QoL in Egyptian children with INS and correlates QoL scores to clinical phenotypes and complications of the disease. Egyptian children with INS need strenuous efforts from pediatricians and psychiatrists to improve QoL. Both PedsQL™ 4.0 scale and GCQ are simple, convenient, and can be used in daily clinical practice to asses QoL in children with NS.
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