Evidence map›Paper›PMID 32016615›Full record

ReviewClinical and experimental medicine2020

Dietary phytochemicals as the potential protectors against carcinogenesis and their role in cancer chemoprevention.

Alena Liskova, Patrik Stefanicka, Marek Samec, Karel Smejkal, Pavol Zubor, Tibor Bielik, Kristina Biskupska-Bodova, Taeg Kyu Kwon, Jan Danko, Dietrich Büsselberg and 5 more

Abstract readReview
PubMed Publisher
In one paragraph

Review in Clinical and experimental medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  4. Frontiers in oncology · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Alena LiskovaDepartment of Obstetrics and Gynecology, Jessenius Faculty of Medicine, Comenius University in Bratislava, Martin, Slovakia.
Patrik StefanickaDepartment of Otorhinolaryngology, Head and Neck Surgery, Faculty of Medicine, Comenius University and University Hospital, Bratislava, Slovakia.
Marek SamecDepartment of Obstetrics and Gynecology, Jessenius Faculty of Medicine, Comenius University in Bratislava, Martin, Slovakia.
Karel SmejkalDepartment of Natural Drugs, Faculty of Pharmacy, University of Veterinary and Pharmaceutical Sciences, Brno, Czech Republic.
Pavol ZuborDepartment of Obstetrics and Gynecology, Jessenius Faculty of Medicine, Comenius University in Bratislava, Martin, Slovakia.
Tibor BielikDepartment of Obstetrics and Gynecology, Jessenius Faculty of Medicine, Comenius University in Bratislava, Martin, Slovakia.
Kristina Biskupska-BodovaDepartment of Obstetrics and Gynecology, Jessenius Faculty of Medicine, Comenius University in Bratislava, Martin, Slovakia.
Taeg Kyu KwonDepartment of Immunology and School of Medicine, Keimyung University, Dalseo-Gu, Daegu, Korea.
Jan DankoDepartment of Obstetrics and Gynecology, Jessenius Faculty of Medicine, Comenius University in Bratislava, Martin, Slovakia.
Dietrich BüsselbergDepartment of Physiology and Biophysics, Weill Cornell Medicine-Qatar, Education City, Qatar Foundation, Doha, Qatar.
Mariusz AdamekDepartment of Thoracic Surgery, Medical University of Silesia, Katowice, Poland.
Luis RodrigoFaculty of Medicine, University of Oviedo, Central University Hospital of Asturias (HUCA), Oviedo, Spain.
Peter Kruzliak2nd Department of Surgery, Faculty of Medicine, Masaryk University and St. Anne's University Hospital, Brno, Czech Republic. kruzliakpeter@gmail.com.ORCID http://orcid.org/0000-0002-7069-3784
Aleksandr ShleikinSchool of Biotechnology and Cryogenic Systems, ITMO University, St. Petersburg, Russia.
Peter KubatkaDepartment of Medical Biology, Jessenius Faculty of Medicine, Comenius University in Bratislava, Mala Hora 4, Martin, 036 01, Slovakia. kubatka@jfmed.uniba.sk.

Funding

Agentúra Ministerstva Školstva, Vedy, Výskumu a Športu SR VEGA 1/0136/19
6 · The paper itself

Abstract

Health-threatening consequences of carcinogen exposure are mediated via occurrence of electrophiles or reactive oxygen species. As a result, the accumulation of biomolecular damage leads to the cancer initiation, promotion or progression. Accordingly, there is an association between lifestyle factors including inappropriate diet or carcinogen formation during food processing, mainstream, second or third-hand tobacco smoke and other environmental or occupational carcinogens and malignant transformation. Nevertheless, increasing evidence supports the protective effects of naturally occurring phytochemicals against carcinogen exposure as well as carcinogenesis in general. Isolated phytochemicals or their mixtures present in the whole plant food demonstrate efficacy against malignancy induced by carcinogens widely spread in our environment. Phytochemicals also minimize the generation of carcinogenic substances during the processing of meat and meat products. Based on numerous data, selected phytochemicals or plant foods should be highly recommended to become a stable and regular part of the diet as the protectors against carcinogenesis.

Indexed as

AnimalsAnticarcinogenic AgentsCarcinogenesisCarcinogensFoodHumansPhytochemicalsAnticarcinogenic AgentsCarcinogensPhytochemicalsAntioxidantCarcinogensChemopreventionDetoxificationDietary phytochemicalsMetabolic activationScavenging effect

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.