Evidence map›Paper›PMID 32015971›Full record

ArticleEuropean journal of case reports in internal medicine2020

Association of Multiple Myeloma and Giant Cell Arteritis - A Case Report.

Rui Marques Osório, Sérgio Pina, Teresa Salero, Margarida Viana Coelho, Domingos Sousa, Catarina Mendonça

Open access · goldAbstract read
In one paragraph

Article in European journal of case reports in internal medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Rui Marques OsórioInternal Medicine Department, Hospital de Faro, Centro Hospitalar do Algarve, Faro, Portugal.
Sérgio PinaInternal Medicine Department, Hospital de Faro, Centro Hospitalar do Algarve, Faro, Portugal.
Teresa SaleroInternal Medicine Department, Hospital de Faro, Centro Hospitalar do Algarve, Faro, Portugal.
Margarida Viana CoelhoInternal Medicine Department, Hospital de Faro, Centro Hospitalar do Algarve, Faro, Portugal.
Domingos SousaInternal Medicine Department, Hospital de Faro, Centro Hospitalar do Algarve, Faro, Portugal.
Catarina MendonçaInternal Medicine Department, Hospital de Faro, Centro Hospitalar do Algarve, Faro, Portugal.
Algarve Biomedical Center · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Autoimmune diseases (AID) have been associated with a variety of lymphoproliferative disorders. Multiple myeloma (MM), one of the most common haematologic malignancies characterized by clonal proliferation of bone marrow plasma cells, has been associated with a range of autoimmune disorders. In this report, we described a case study of a patient admitted to our Internal Medicine Department for a bone marrow biopsy and myelogram due to a monoclonal peak observed by his general practitioner. However, at admission he presented typical giant cell arteritis (GCA) complaints, suggesting the coexistence of both diseases. The possible pathogenesis, as found in the literature, explaining the association will be discussed. LEARNING POINTS: A relationship between AID and lymphoproliferative diseases, although rare, may occur and some studies suggest that the diagnosis of autoimmune disease has a negative impact on survival in MM patients.Bone marrow plasmacytosis can present a diagnostic dilemma, since it may be due to neoplastic or non-neoplastic conditions (that is, reactive plasmacytosis associated with AID, chronic infection, metastatic carcinoma, liver diseases and acquired immunodeficiency).Immunophenotyping in a myelogram or immunohistochemistry in bone marrow studies are useful in confirming a monoclonal plasma cell proliferation.

Indexed as

autoimmunityGiant cell arteritismultiple myeloma

Identifiers

PMID32015971
PMCPMC6993903
OpenAlexW3007366296

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.