Evidence map›Paper›PMID 32015690›Full record

ReviewCancer cell international2020

The heterogeneous clinical and pathological landscapes of metastatic

Giuseppe Nicolò Fanelli, Carlo Alberto Dal Pozzo, Ilaria Depetris, Marta Schirripa, Stefano Brignola, Paola Biason, Mariangela Balistreri, Luca Dal Santo, Sara Lonardi, Giada Munari and 2 more

Abstract readReview
In one paragraph

Review in Cancer cell international, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
58citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

58 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
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  13. Real-world characteristics and outcomes of patients with BRAFESMO real world data and digital oncology · 2025
    Article
  14. Review
  15. Expert consensus on the optimal management of BRAFAsia-Pacific journal of clinical oncology · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Giuseppe Nicolò Fanelli *1Surgical Pathology Unit, Department of Medicine (DIMED), University of Padua, via Gabelli 61, 35121 Padua, Italy.
Carlo Alberto Dal Pozzo *1Surgical Pathology Unit, Department of Medicine (DIMED), University of Padua, via Gabelli 61, 35121 Padua, Italy.
Ilaria Depetris *2Department of Oncology, Veneto Institute of Oncology IOV-IRCCS, Padua, Italy.
Marta Schirripa2Department of Oncology, Veneto Institute of Oncology IOV-IRCCS, Padua, Italy.
Stefano Brignola1Surgical Pathology Unit, Department of Medicine (DIMED), University of Padua, via Gabelli 61, 35121 Padua, Italy.
Paola Biason2Department of Oncology, Veneto Institute of Oncology IOV-IRCCS, Padua, Italy.
Mariangela Balistreri1Surgical Pathology Unit, Department of Medicine (DIMED), University of Padua, via Gabelli 61, 35121 Padua, Italy.
Luca Dal Santo1Surgical Pathology Unit, Department of Medicine (DIMED), University of Padua, via Gabelli 61, 35121 Padua, Italy.
Sara Lonardi2Department of Oncology, Veneto Institute of Oncology IOV-IRCCS, Padua, Italy.
Giada Munari1Surgical Pathology Unit, Department of Medicine (DIMED), University of Padua, via Gabelli 61, 35121 Padua, Italy.
Fotios Loupakis *2Department of Oncology, Veneto Institute of Oncology IOV-IRCCS, Padua, Italy.
Matteo Fassan *1Surgical Pathology Unit, Department of Medicine (DIMED), University of Padua, via Gabelli 61, 35121 Padua, Italy.ORCID 0000-0001-6515-5482

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Colorectal cancer (CRC) is a complex and molecularly heterogeneous disease representing one of the most frequent causes of cancer-related death worldwide. About 8-15% of CRCs harbor a mutation in

Indexed as

BRAF mutationColorectal cancerPersonalized medicineSequencing

Identifiers

PMID32015690
PMCPMC6990491

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.