ArticleNature2020
A new coronavirus associated with human respiratory disease in China.
Erratum issued 11 registry-linked trialsOpen access · hybridAbstract readCase Reports
In one paragraph
Article in Nature, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to 11 registered trials, which are not on this map. Cited by 6,147 papers, 4 of them syntheses that pooled it.
0numbers the graph read from it
0cells of the map it votes in
6,147citing papers in PubMed, 4 pooled it
292.7field-weighted citation impact, top 1% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Phase I/II Study of Universal Off-the-shelf NKG2D-ACE2 CAR-NK Cells Secreting IL15 Superagonist and GM-CSF-neutralizing scFv for Therapy of COVID-19
Treatment of Severe and Critical COVID-19 Pneumonia With Convalescent Plasma
Intravenous Immunoglobulins for the Treatment of Covid-19 Patients: a Clinical Trial
Gender Differences in Stroke With COVID-19: Epigenetic and Biochemical Study of ACE2 Receptor and Relationship With Rehabilitative Outcome
Organizational Impact of Rapid Screening for COVID-19 by Delocalized Biology in the Birth Room
Phase II Study to Evaluate Immunogenicity and Safety in Subjects With Evidence of Prior Immunity to SARS-CoV-2 of a Single Intramuscular or Intranasal Dose of the Live Recombinant Newcastle Disease Virus Based AVX/COVID-12 Vaccine
NCT05507671 phase3active not recruitingnot on this mapstarted 2021, after this paper: background citation
The Role of the Bacillus Calmette-Guérin Vaccine (BCG) in the Clinical Evolution of COVID-19 and in the Efficacy of Anti-SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2) Vaccines
NCT05710783 phase2 / phase3completednot on this mapstarted 2022, after this paper: background citation
Phase II/III Parallel, Double-blind, Non-inferiority Study With Active Control, to Evaluate the Immunogenicity and Safety of a Booster Immunization Scheme With a Single Intramuscular Dose of the Recombinant Vaccine Against SARS-CoV-2
Efficacy of SARS-COV-2 Detection From Used Surgical Mask Compared to Standard Detection Method
Monitoring of Antimicrobial Resistance Based on Metagenomics Analyses in Pneumonia Patients: a Genomic Epidemiology Study
Total Infectome Characterization of Eye Infections: a Metagenomic Sequencing Based Observational Study
Who cites it
6,147 citing papers in PubMed, 4 syntheses or guidelines pooled it, 12,814 citations in OpenAlex.
- A Systematic Review of Methodological Approaches to SARS-CoV-2 Wastewater Surveillance.Viruses · 2026Pooled it
- From immunological mechanisms to targeted therapies: a bibliometric analysis in the domain of research concerning neutrophil extracellular traps and pulmonary diseases (2006-2025).Frontiers in immunology · 2026Pooled it
- Viral etiology of acute respiratory infections in Sub-Saharan Africa during the pre-COVID-19 period (2006-2019): a systematic review and meta-analysis.BMC infectious diseases · 2025Pooled it
- Association between Guillain-Barré syndrome and SARS-CoV-2 virus infection, including the impact of COVID-19 vaccination in the context of the development and general clinical characteristics of the disease.Journal of neurovirology · 2025Pooled it
- Infliximab Pharmacokinetics, Dosing, and Response in Hospitalized Patients with COVID-19 Pneumonia: A Secondary Analysis of a Multinational Randomized Clinical Trial (ACTIV-1 IM).Journal of clinical pharmacology · 2025Trial
- Gapmers targeting conserved SARS-CoV-2 single-stranded regions reduce viral load and reshape inflammatory macrophage responses.iScience · 2026Article
- Voluntary wheel running behavior is reduced by SARS-CoV-2 S1 administration and mitigates hypothalamic neuroinflammatory processes.Brain, behavior, & immunity - health · 2026Article
- mRNA Vaccines Targeting the Conserved SARS-CoV-2 Fusion Machinery Elicit Cross-Variant and Robust Immunity.Vaccines · 2026Article
- SARS-CoV-2 intra-host variation shows evidence of transmission and convergent evolution in a university surveillance cohort.Microbial genomics · 2026Article
- SARS-CoV-2 Delta variant-specific ORF3a mutations destabilize lysosomal homeostasis to trigger lysosomal damage-mediated cell death.Communications biology · 2026Article
- Supplementation of αKG along with TGFβ/HIF1α antagonist rescues lung fibrosis in mice with severe SARS-CoV-2 infection.Journal of translational medicine · 2026Article
- Peptides containing SARS-CoV-2 spike-protein residues are antagonists of α7 and α9α10 nAChRs and modulate interleukin-1β release from human monocytic THP-1 cells.The Journal of biological chemistry · 2026Article
- Repurposing drug screen for the identification of helicase inhibitors from viruses of pandemic concern.SLAS discovery : advancing life sciences R & D · 2026Article
- Virus reactivation in acute and long COVID-19.Nature · 2026Article
- Beneficial Effect of COVID-19 Vaccination on Decreased Pulmonary Vascular and Airway Volumes of Patients with Long-COVID Syndrome.Medical sciences (Basel, Switzerland) · 2026Article
- Genetic diversity of pangolin coronaviruses reveals a key immuno-evasive substitution at spike residue 519.Journal of virology · 2026Article
- Classification of SARS-CoV-2 Variants Through the Epistatic Circos Plots with Convolutional Neural Networks.Journal of molecular evolution · 2026Article
- Decoding Enzyme-Inhibitor Kinetic Mechanisms by Isothermal Titration Calorimetry: The Case of SARS-CoV-2 3CLAnalytical chemistry · 2026Article
- Folic Acid and Endothelial Dysfunction in COVID-19.Life (Basel, Switzerland) · 2026Review
- Temporal Dynamics of Innate Immune Activation and Viral Interference During Sequential Co-Infection with Influenza A Virus and SARS-CoV-2: Molecular Mechanisms, Clinical Evidence, and Therapeutic Implications.International journal of molecular sciences · 2026Review
6,087 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
19 authors at 5 institutions in 2 countries.
Fan Wu *Shanghai Public Health Clinical Center, Fudan University, Shanghai, China.
Su Zhao *Department of Pulmonary and Critical Care Medicine, The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Bin Yu *Wuhan Center for Disease Control and Prevention, Wuhan, China.
Yan-Mei Chen *Shanghai Public Health Clinical Center, Fudan University, Shanghai, China.
Wen Wang *Department of Zoonosis, National Institute for Communicable Disease Control and Prevention, China Center for Disease Control and Prevention, Beijing, China.
Zhi-Gang Song *Shanghai Public Health Clinical Center, Fudan University, Shanghai, China.
Yi Hu *Department of Pulmonary and Critical Care Medicine, The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.ORCID http://orcid.org/0000-0002-2882-5210
Zhao-Wu TaoDepartment of Pulmonary and Critical Care Medicine, The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Jun-Hua TianWuhan Center for Disease Control and Prevention, Wuhan, China.
Yuan-Yuan PeiShanghai Public Health Clinical Center, Fudan University, Shanghai, China.
Ming-Li YuanDepartment of Pulmonary and Critical Care Medicine, The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Yu-Ling ZhangShanghai Public Health Clinical Center, Fudan University, Shanghai, China.
Fa-Hui DaiShanghai Public Health Clinical Center, Fudan University, Shanghai, China.
Yi LiuShanghai Public Health Clinical Center, Fudan University, Shanghai, China.
Qi-Min WangShanghai Public Health Clinical Center, Fudan University, Shanghai, China.
Jiao-Jiao ZhengShanghai Public Health Clinical Center, Fudan University, Shanghai, China.
Lin XuShanghai Public Health Clinical Center, Fudan University, Shanghai, China.
Edward C HolmesShanghai Public Health Clinical Center, Fudan University, Shanghai, China.ORCID http://orcid.org/0000-0001-9596-3552
Yong-Zhen ZhangShanghai Public Health Clinical Center, Fudan University, Shanghai, China. zhangyongzhen@shphc.org.cn.
Shanghai Public Health Clinical Center · CNCentral Hospital of Wuhan · CNWuhan Center for Disease Control and Prevention · CNNational Institute for Communicable Disease Control and Prevention · CNThe University of Sydney · AU
Funding
No grant is acknowledged in the PubMed record.
Abstract
Emerging infectious diseases, such as severe acute respiratory syndrome (SARS) and Zika virus disease, present a major threat to public health
Indexed as
AdultBetacoronavirusChinaCommunicable Diseases, EmergingCoronavirus InfectionsCOVID-19Genome, ViralHumansLungMalePhylogenyPneumonia, ViralRecombination, GeneticRNA, ViralSARS-CoV-2Severe Acute Respiratory SyndromeRNA, Viral
Identifiers
What OpenQuestion holds
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LicenceCC BY
Read underepoch 390
Registered trials
NCT04324996ClinicalTrials.gov
NCT04432103ClinicalTrials.gov
NCT04548557ClinicalTrials.gov
NCT04766645ClinicalTrials.gov
NCT05175716ClinicalTrials.gov
NCT05205746ClinicalTrials.gov
and 5 more above
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.