ArticleExperimental & molecular medicine2020
Isocitrate dehydrogenase 2 protects mice from high-fat diet-induced metabolic stress by limiting oxidative damage to the mitochondria from brown adipose tissue.
Erratum issuedOpen access · goldAbstract read
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Article in Experimental & molecular medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 37 papers.
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37citing papers in PubMed
4.3field-weighted citation impact, top 5% of its field
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Who cites it
37 citing papers in PubMed, 71 citations in OpenAlex.
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- IDH2 regulates macrophage polarization and tumorigenesis by modulating mitochondrial metabolism in macrophages.Molecular medicine (Cambridge, Mass.) · 2024Article
- Modulation of Sirtuin 3 by N-Acetylcysteine Preserves Mitochondrial Oxidative Phosphorylation and Restores Bisphenol A-Induced Kidney Damage in High-Fat-Diet-Fed Rats.Current issues in molecular biology · 2024Article
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- Global gene expression profiling of perirenal brown adipose tissue whitening in goat kids reveals novel genes linked to adipose remodeling.Journal of animal science and biotechnology · 2024Article
- Childhood obesity, metabolic syndrome, and oxidative stress: microRNAs go on stage.Reviews in endocrine & metabolic disorders · 2023Review
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Corrections and comments
- Erratum issued
Authors and funding
17 authors at 9 institutions in 2 countries.
Jae-Ho LeeDepartment of Physiology, Keimyung University School of Medicine, Daegu, 42601, Republic of Korea.
Younghoon GoDepartment of Internal Medicine, School of Medicine Kyungpook National University, Kyungpook National University Hospital, Daegu, 41944, Republic of Korea.
Do-Young KimDepartment of Physiology, Keimyung University School of Medicine, Daegu, 42601, Republic of Korea.
Sun Hee LeeDepartment of Physiology, Keimyung University School of Medicine, Daegu, 42601, Republic of Korea.
Ok-Hee KimDepartment of Physiology, Lee Gil Ya Cancer and Diabetes Institute, Gachon University School of Medicine, Younsoo-gu, Inchon, 21999, Republic of Korea.
Yong Hyun JeonLaboratory Animal Center, Daegu-Gyeongbuk Medical Innovation Foundation, Daegu, 41061, Republic of Korea.
Taeg Kyu KwonDepartment of Immunology, Keimyung University School of Medicine, Daegu, 42601, Republic of Korea.
Jae-Hoon BaeDepartment of Physiology, Keimyung University School of Medicine, Daegu, 42601, Republic of Korea.
Dae-Kyu SongDepartment of Physiology, Keimyung University School of Medicine, Daegu, 42601, Republic of Korea.ORCID http://orcid.org/0000-0002-6749-3538
Im Joo RhyuDepartment of Anatomy, Korea University College of Medicine, Seoul, 02841, Republic of Korea.
In-Kyu LeeDepartment of Internal Medicine, School of Medicine Kyungpook National University, Kyungpook National University Hospital, Daegu, 41944, Republic of Korea.
Minho ShongResearch Center for Endocrinology and Metabolism, Chungnam National University Hospital (CNUH), 282 Munhwaro, Daejeon, 35015, Republic of Korea.
Byung-Chul OhDepartment of Physiology, Lee Gil Ya Cancer and Diabetes Institute, Gachon University School of Medicine, Younsoo-gu, Inchon, 21999, Republic of Korea.
Christopher PetucciCenter for Metabolic Origins of Disease, Sanford Burnham Prebys Medical Discovery Institute, Orlando, FL, 32827, USA.
Jeen-Woo ParkSchool of Life Sciences and Biotechnology, College of Natural Science, Kyungpook National University, Daegu, 41566, Republic of Korea.
Timothy F OsborneInstitute for Fundamental Biomedical Research, Department of Medicine and Biological Chemistry, Johns Hopkins University School of Medicine, St. Petersburg, FL, 33701, USA.
Seung-Soon ImDepartment of Physiology, Keimyung University School of Medicine, Daegu, 42601, Republic of Korea. ssim73@kmu.ac.kr.ORCID http://orcid.org/0000-0002-2743-2108
Keimyung University · KRGachon University · KRKyungpook National University Hospital · KRChungnam National University Hospital · KRDaegu-Gyeongbuk Medical Innovation Foundation · KRJohns Hopkins University · USKorea University · KRKyungpook National University · KRSanford Burnham Prebys Medical Discovery Institute · US
Funding
Sterol Regulatory Element Binding Proteins in Regulation of Lipid MetabolismR01HL048044 · NHLBI · UNIVERSITY OF CALIFORNIA-IRVINE · PI OSBORNE, TIMOTHY F · 1993 to 2017
$7.3MPROVIDE RABBITS, RATS MICE, HAMSTERS GERBILS, GUINEA PIGS27307C0012 · NIEHS · PI BOLEN, WAYNE · 2007 to 2007
$1.0MKorea Health Industry Development Institute (KHIDI) HI16C1501Korea Health Industry Development Institute (KHIDI) HR18C0012Ministry of Science, ICT and Future Planning (MSIP) 2016R1A2B4008516National Research Foundation of Korea (NRF) 2014R1A5A2010008National Research Foundation of Korea (NRF) 2015R1D1A1AO1057610National Research Foundation of Korea (NRF) 2017R1A2B3006406NHLBI NIH HHS R01 HL048044NIEHS NIH HHS 27307C0012
Abstract
Isocitrate dehydrogenase 2 (IDH2) is an NADP
Indexed as
Adipose Tissue, BrownAnimalsAntioxidantsDiet, High-FatIsocitrate DehydrogenaseMaleMiceMice, Inbred C57BLMitochondriaNADPOrganelle BiogenesisOxidation-ReductionOxidative StressReactive Oxygen SpeciesStress, PhysiologicalAntioxidantsIsocitrate Dehydrogenaseisocitrate dehydrogenase 2, mouseNADPReactive Oxygen Species
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY
Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.