ArticleScientific reports2020
Resistance to change: AMR gene dynamics on a commercial pig farm with high antimicrobial usage.
Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed.
- KEGG orthology-based machine learning reveals functional determinants of antimicrobial resistance inMicrobiology spectrum · 2026Article
- Changes in antimicrobial resistance profiles of Escherichia coli and the metagenome on Dutch pig farms after antimicrobial usage interventions.npj antimicrobials and resistance · 2026Article
- Airborne Movement of Antibiotic Resistance Genes Between Livestock Stables and Farmers' Homes.Microorganisms · 2026Article
- Antimicrobial use and Escherichia coli resistance patterns in Hungarian pig farms: a data-driven farm-level analysis.Scientific reports · 2026Article
- Temporal dynamics of the resistome in gilts raised in an organic operation in which semen used for artificial insemination is the primary source of antimicrobial exposure.Scientific reports · 2025Article
- Impact of Organic and Conventional Husbandry Systems on the Gut Microbiome and Resistome in Pigs.Microorganisms · 2025Article
- Antimicrobial resistance genes in weaned pigs: quantitative abundance and group dynamics assessed by qPCR.Frontiers in veterinary science · 2025Article
- Florfenicol administration in piglets co-selects for multiple antimicrobial resistance genes.mSystems · 2024Article
- Antimicrobial Susceptibility of CommensalAnimals : an open access journal from MDPI · 2024Article
- Effects of dietary zinc on the gut microbiome and resistome of the gestating cow and neonatal calf.Animal microbiome · 2024Article
- Gut microbiome and resistome characterization of pigs treated with commonly used post-weaning diarrhea treatments.Animal microbiome · 2024Article
- Dispersion of antimicrobial resistant bacteria in pig farms and in the surrounding environment.Animal microbiome · 2024Article
- An economic assessment of alternative antimicrobial use scenarios on pig farms.Frontiers in veterinary science · 2024Article
- Metagenomic comparison of the faecal and environmental resistome on Irish commercial pig farms with and without zinc oxide and antimicrobial usage.Animal microbiome · 2023Article
- The gut microbiome and resistome of conventionally vs. pasture-raised pigs.Microbial genomics · 2023Article
- Insights on the effects of antimicrobial and heavy metal usage on the antimicrobial resistance profiles of pigs based on culture-independent studies.Veterinary research · 2023Review
- Age influences the temporal dynamics of microbiome and antimicrobial resistance genes among fecal bacteria in a cohort of production pigs.Animal microbiome · 2023Article
- Gut Microbiome Studies in Livestock: Achievements, Challenges, and Perspectives.Animals : an open access journal from MDPI · 2022Review
- Distribution and Characterization of Antimicrobial Resistant Pathogens in a Pig Farm, Slaughterhouse, Meat Processing Plant, and in Retail Stores.Microorganisms · 2022Article
- High-quality metagenome-assembled genomes from proximal colonic microbiomes of synbiotic-treated korean native black pigs reveal changes in functional capacity.Scientific reports · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
Group antimicrobial administration is used to control disease in livestock, but we have little insight into how this impacts antimicrobial resistance (AMR) gene dynamics. Here, a longitudinal study was carried out during a single production cycle on a commercial pig unit with high historic and current antimicrobial usage. Quantitative PCR, 16S rRNA gene metabarcoding and shotgun metagenomic sequencing were used to track faecal AMR gene abundance and diversity and microbiome alpha diversity. Shotgun metagenomic sequencing identified 144 AMR genes in total, with higher AMR gene diversity present in young pigs compared to dry sows. Irrespective of in-feed antibiotic treatment or changes in microbiome diversity, mean AMR gene copy number was consistently high, with some AMR genes present at copy numbers comparable to the bacterial 16S rRNA gene. In conclusion, AMR gene prevalence and abundance were not influenced by antibiotic use, either during the production cycle or following whole-herd medication. The high levels of certain genes indicate they are widely disseminated throughout the microbial population, potentially aiding stability. Despite the high and relatively stable levels of resistance genes against the main antimicrobials used, these compounds continue to control production limiting diseases on this unit.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.