Evidence map›Paper›PMID 32015354›Full record

ArticleScientific reports2020

Standardized phylogenetic and molecular evolutionary analysis applied to species across the microbial tree of life.

Migun Shakya, Sanaa A Ahmed, Karen W Davenport, Mark C Flynn, Chien-Chi Lo, Patrick S G Chain

Abstract read
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 78 papers.

0numbers the graph read from it
0cells of the map it votes in
78citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

78 citing papers in PubMed.

  1. Article
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  10. Imported, not invented, genes prevail amongProceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Strain-Level Differences ofJournal of microbiology and biotechnology · 2025
    Article
  16. Article
  17. Article
  18. Article
  19. Machine Learning-Based Characterization ofPathogens (Basel, Switzerland) · 2025
    Article
  20. Review

18 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Migun ShakyaBioscience Division, Los Alamos National Laboratory, MS-M888, Los Alamos, NM, 87545, USA. migun@lanl.gov.ORCID http://orcid.org/0000-0003-3876-691X
Sanaa A AhmedBioscience Division, Los Alamos National Laboratory, MS-M888, Los Alamos, NM, 87545, USA.
Karen W DavenportBioscience Division, Los Alamos National Laboratory, MS-M888, Los Alamos, NM, 87545, USA.ORCID http://orcid.org/0000-0002-2740-1344
Mark C FlynnBioscience Division, Los Alamos National Laboratory, MS-M888, Los Alamos, NM, 87545, USA.
Chien-Chi LoBioscience Division, Los Alamos National Laboratory, MS-M888, Los Alamos, NM, 87545, USA.
Patrick S G ChainBioscience Division, Los Alamos National Laboratory, MS-M888, Los Alamos, NM, 87545, USA. pchain@lanl.gov.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There is growing interest in reconstructing phylogenies from the copious amounts of genome sequencing projects that target related viral, bacterial or eukaryotic organisms. To facilitate the construction of standardized and robust phylogenies for disparate types of projects, we have developed a complete bioinformatic workflow, with a web-based component to perform phylogenetic and molecular evolutionary (PhaME) analysis from sequencing reads, draft assemblies or completed genomes of closely related organisms. Furthermore, the ability to incorporate raw data, including some metagenomic samples containing a target organism (e.g. from clinical samples with suspected infectious agents), shows promise for the rapid phylogenetic characterization of organisms within complex samples without the need for prior assembly.

Indexed as

SoftwareAlgorithmsBiological EvolutionBurkholderiaChromosome MappingComputational BiologyDatasets as TopicEbolavirusEscherichiaEvolution, MolecularHigh-Throughput Nucleotide SequencingMetagenomePhylogenySaccharomycesSoftware Validation

Identifiers

PMID32015354
PMCPMC6997174

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.