ArticleMedical science monitor : international medical journal of experimental and clinical research2020
Age-Related Decline in Renal Blood Flow Could Be a Beneficial and Compensatory Mechanism.
Article in Medical science monitor : international medical journal of experimental and clinical research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
7 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.
- Comparing robotic and open partial nephrectomy under the prism of surgical precision: a meta-analysis of the average blood loss rate as a novel variable.Journal of robotic surgery · 2024Pooled it
- Immediate effects of Thai foot massage on renal blood flow, psychological stress, and heart rate variability in community-dwelling older adults: a randomized controlled trial.F1000Research · 2024Trial
- Risk of Rhabdomyolysis and Kidney Injury after Intensive Exercise. Potential of Novel Biomarkers of Kidney Injury: A Narrative Review.Journal of human kinetics · 2026Review
- Association of renal regional tissue oxygen saturation and post-procedural acute kidney injury following transcatheter aortic valve implantation.Journal of clinical monitoring and computing · 2025Observational
- Chronic kidney disease and aging: dissecting the p53/p21 pathway as a therapeutic target.Biogerontology · 2024Review
- Selection of a suitable animal model to evaluate secretion of drugs in the human milk: a systematic approach.Xenobiotica; the fate of foreign compounds in biological systems · 2024Article
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Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Aging is a time-dependent process affecting all organs and tissues in the human body. The process of aging in the kidney is characterized by structural and functional changes, of which the main feature is a reduction in size, a decreased number of functioning glomeruli, and vascular changes. These changes result in functional deterioration, mainly involving a decrease in renal blood flow and the glomerular filtration rate. Additionally, impaired regulation of electrolyte and water homeostasis due to structural changes in the tubulo-interstitial system can occur. A reduced glomerular filtration rate does not necessarily result in serious clinical complications, and other selected parameters of kidney function may remain within reference value ranges in the elderly. Aging is also accompanied by decreased perfusion of other organs, including the heart and brain, which can induce more serious conditions in the elderly, including cardiac insufficiency or impairment of mental function. Thus, the decrease in renal blood flow in the aging kidney could be regarded as a compensatory mechanism to maintain perfusion of other organs and therefore, it could be also treated as being a beneficial reordering of blood-flow allocation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.