ArticleProceedings of the National Academy of Sciences of the United States of America2020
Shape-preserving amorphous-to-crystalline transformation of CaCO
Article in Proceedings of the National Academy of Sciences of the United States of America, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed, 132 citations in OpenAlex.
- Navigating Classical and Nonclassical Realms of Nucleation and Crystallization.Small (Weinheim an der Bergstrasse, Germany) · 2026Review
- The Role of Confinement in Biomineralization.Chemical reviews · 2025Review
- Long-acting IL-2 release from pressure-fused biomineral tablets promotes antitumor immune response.Nature cancer · 2025Article
- Biomineral tablets for long-acting IL-2 immunotherapy.Nature cancer · 2025Article
- Surface Free Energies and Entropy of Aqueous CaCOLangmuir : the ACS journal of surfaces and colloids · 2025Article
- Formation, chemical evolution and solidification of the dense liquid phase of calcium (bi)carbonate.Nature materials · 2025Article
- Exploring Biomineralization Processes Using In Situ Liquid Transmission Electron Microscopy: A Review.Small (Weinheim an der Bergstrasse, Germany) · 2025Review
- Fabrication of oxygen-releasing dextran microgels by droplet-based microfluidic method.RSC advances · 2024Article
- Article
- Triggered metabolism of adenosine triphosphate as an explanation for the chemical heterogeneity of heterotopic ossification.Communications chemistry · 2023Article
- Assessing an aqueous flow cell designed for in situ crystal growth under X-ray nanotomography and effects of radiolysis products.Journal of synchrotron radiation · 2023Article
- Growth dynamics and amorphous-to-crystalline phase transformation in natural nacre.Nature communications · 2023Article
- The Kinetics of Aragonite Formation from Solution via Amorphous Calcium Carbonate.Nanomaterials (Basel, Switzerland) · 2022Article
- Structure of an amorphous calcium carbonate phase involved in the formation ofProceedings of the National Academy of Sciences of the United States of America · 2022Article
- Crystal nucleation: Rare made common and captured by Raman.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Biomineralized Materials as Model Systems for Structural Composites: Intracrystalline Structural Features and Their Strengthening and Toughening Mechanisms.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2022Review
- Particle-based hematite crystallization is invariant to initial particle morphology.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- In situ imaging of amorphous intermediates during brucite carbonation in supercritical CONature materials · 2022Article
- Otolith chemoscape analysis in whiting links fishing grounds to nursery areas.Communications biology · 2020Article
- In situ imaging of two-dimensional surface growth reveals the prevalence and role of defects in zeolite crystallization.Proceedings of the National Academy of Sciences of the United States of America · 2020Article
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Authors and funding
8 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Organisms use inorganic ions and macromolecules to regulate crystallization from amorphous precursors, endowing natural biominerals with complex morphologies and enhanced properties. The mechanisms by which modifiers enable these shape-preserving transformations are poorly understood. We used in situ liquid-phase transmission electron microscopy to follow the evolution from amorphous calcium carbonate to calcite in the presence of additives. A combination of contrast analysis and infrared spectroscopy shows that Mg ions, which are widely present in seawater and biological fluids, alter the transformation pathway in a concentration-dependent manner. The ions bring excess (structural) water into the amorphous bulk so that a direct transformation is triggered by dehydration in the absence of morphological changes. Molecular dynamics simulations suggest Mg-incorporated water induces structural fluctuations, allowing transformation without the need to nucleate a separate crystal. Thus, the obtained calcite retains the original morphology of the amorphous state, biomimetically achieving the morphological control of crystals seen in biominerals.
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