Evidence map›Paper›PMID 32015097›Full record

ArticleeNeuro

Concentration-Dependent Recruitment of Mammalian Odorant Receptors.

Xiaoyang Serene Hu, Kentaro Ikegami, Aashutosh Vihani, Kevin W Zhu, Marcelo Zapata, Claire A de March, Matthew Do, Natasha Vaidya, Gary Kucera, Cheryl Bock and 3 more

Open access · goldAbstract read
In one paragraph

Article in eNeuro. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Recalibrating Olfactory Neuroscience to the Range of Naturally Occurring Odor Concentrations.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Review
  6. Article
  7. Experience-dependent plasticity in the olfactory system ofFrontiers in cellular neuroscience · 2023
    Review
  8. Article
  9. Sensory Perception of Non-Deuterated and Deuterated Organic Compounds.Chemistry (Weinheim an der Bergstrasse, Germany) · 2021
    Article
  10. Review
  11. Article
  12. Encoding the Odor of Cigarette Smoke.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2020
    Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 2 countries.

Xiaoyang Serene HuDepartment of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, NC 27710.
Kentaro IkegamiDepartment of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, NC 27710.
Aashutosh VihaniDepartment of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, NC 27710.ORCID 0000-0001-5979-101X
Kevin W ZhuDepartment of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, NC 27710.ORCID 0000-0001-7664-7204
Marcelo ZapataDepartment of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, NC 27710.
Claire A de MarchDepartment of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, NC 27710.
Matthew DoDepartment of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, NC 27710.
Natasha VaidyaDepartment of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, NC 27710.
Gary KuceraDCI Rodent Cancer Models Shared Resource, Duke University Medical Center, Durham, NC 27710.
Cheryl BockDCI Rodent Cancer Models Shared Resource, Duke University Medical Center, Durham, NC 27710.
Yue JiangDepartment of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, NC 27710.
Masafumi YohdaTokyo University of Agriculture and Technology, Tokyo 183-8538, Japan.ORCID 0000-0001-8307-9671
Hiroaki MatsunamiDepartment of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, NC 27710 hiroaki.matsunami@duke.edu.ORCID 0000-0002-8850-2608
Duke Medical Center · USDuke University · USTokyo University of Agriculture and Technology · JP

Funding

Peripheral Odor Coding in MammalsR01DC014423 · NIDCD · DUKE UNIVERSITY · PI MATSUNAMI, HIROAKI · 2015 to 2019
$2.3M
Biogenesis of olfactory G protein-coupled receptorsR01DC016224 · NIDCD · DUKE UNIVERSITY · PI MATSUNAMI, HIROAKI · 2017 to 2021
$2.2M
High-throughput mapping of olfactory receptor identity to olfactory bulb glomeruliF31DC017394 · NIDCD · DUKE UNIVERSITY · PI ZHU, KEVIN WILLIAM · 2018 to 2020
$110k
NIDCD NIH HHS F31 DC017394NIDCD NIH HHS R01 DC014423NIDCD NIH HHS R01 DC016224
6 · The paper itself

Abstract

A fundamental challenge in studying principles of organization used by the olfactory system to encode odor concentration information has been identifying comprehensive sets of activated odorant receptors (ORs) across a broad concentration range inside freely behaving animals. In mammals, this has recently become feasible with high-throughput sequencing-based methods that identify populations of activated ORs

Indexed as

Olfactory Receptor NeuronsReceptors, OdorantAnimalsMammalsOdorantsOlfactory BulbSmellReceptors, Odorantchemical sensesGPCRodorolfactorysmell

Identifiers

PMID32015097
PMCPMC7189481
OpenAlexW3002017017

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.