Evidence map›Paper›PMID 32015027›Full record

ArticleAntimicrobial agents and chemotherapy2020

Activation of Heme Oxygenase Expression by Cobalt Protoporphyrin Treatment Prevents Pneumonic Plague Caused by Inhalation of

Joshua L Willix, Jacob L Stockton, Rachel M Olson, Paul E Anderson, Deborah M Anderson

Abstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Joshua L WillixDepartment of Veterinary Pathobiology and the Laboratory for Infectious Disease Research, University of Missouri, Columbia, Missouri, USA.
Jacob L StocktonDepartment of Veterinary Pathobiology and the Laboratory for Infectious Disease Research, University of Missouri, Columbia, Missouri, USA.
Rachel M OlsonDepartment of Veterinary Pathobiology and the Laboratory for Infectious Disease Research, University of Missouri, Columbia, Missouri, USA.
Paul E AndersonDepartment of Veterinary Pathobiology and the Laboratory for Infectious Disease Research, University of Missouri, Columbia, Missouri, USA.
Deborah M AndersonDepartment of Veterinary Pathobiology and the Laboratory for Infectious Disease Research, University of Missouri, Columbia, Missouri, USA andersondeb@missouri.edu.

Funding

Development of a Host Targeted Therapeutic for Pneumonic PlagueR21AI133450 · NIAID · UNIVERSITY OF MISSOURI-COLUMBIA · PI ANDERSON, DEBORAH M · 2018 to 2019
$398k
NIAID NIH HHS R21 AI133450
6 · The paper itself

Abstract

Pneumonic plague, caused by the Gram-negative bacteria

Indexed as

AerosolsAnimalsAnti-Bacterial AgentsBronchopneumoniaDisease Models, AnimalDoxycyclineDrug Therapy, CombinationFemaleHeme Oxygenase-1HumansLungMaleMiceMice, Inbred C57BLPlagueProtoporphyrinsAerosolsAnti-Bacterial AgentscobaltiprotoporphyrinDoxycyclineHeme Oxygenase-1HMOX1 protein, humanProtoporphyrinscobalt protoporphyrindoxycyclineheme oxygenaseplaguepneumoniasepsisYersinia pestis

Identifiers

PMID32015027
PMCPMC7179272

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.