Evidence map›Paper›PMID 32015022›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2020

Intrinsic Excitability Increase in Cerebellar Purkinje Cells after Delay Eye-Blink Conditioning in Mice.

Heather K Titley, Gabrielle V Watkins, Carmen Lin, Craig Weiss, Michael McCarthy, John F Disterhoft, Christian Hansel

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 72 citations in OpenAlex.

  1. Article
  2. Flexible Coupling of Synaptic and Intrinsic Plasticity in a Cerebellar Circuit.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026
    Article
  3. Article
  4. A Novel Mouse Model for Developmental and Epileptic Encephalopathy by Purkinje Cell-Specific Deletion ofThe Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Heather K TitleyDepartment of Neurobiology, University of Chicago, Chicago, Illinois 60637, and.
Gabrielle V WatkinsDepartment of Neurobiology, University of Chicago, Chicago, Illinois 60637, and.
Carmen LinDepartment of Physiology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611.
Craig WeissDepartment of Physiology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611.ORCID 0000-0002-9861-8727
Michael McCarthyDepartment of Physiology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611.
John F DisterhoftDepartment of Physiology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611.ORCID 0000-0002-8817-7913
Christian HanselDepartment of Neurobiology, University of Chicago, Chicago, Illinois 60637, and chansel@bsd.uchicago.edu.
Northwestern University · USUniversity of Chicago · USUniversity of Illinois Chicago · US

Funding

SLOW OUTWARD CURRENTS AND LEARNING IN AGING HIPPOCAMPUSR37AG008796 · NIA · NORTHWESTERN UNIVERSITY AT CHICAGO · PI DISTERHOFT, JOHN F · 1999 to 2020
$9.2M
University of Chicago Initiative for Maximizing Student Development (IMSD) - Renewal 01R25GM109439 · NIGMS · UNIVERSITY OF CHICAGO · PI SCHWARTZ, NANCY B · 2014 to 2023
$5.7M
Intrinsic Plasticity and Information Storage in Cerebellar Purkinje CellsR01NS062771 · NINDS · UNIVERSITY OF CHICAGO · PI HANSEL, CHRISTIAN ROBERT · 2008 to 2023
$5.2M
Training in Emerging Multidisciplinary Approaches to Mental Health and DiseaseT32MH020065 · NIMH · UNIVERSITY OF CHICAGO · PI NICOLAE, DAN LIVIU, RZHETSKY, ANDREY · 2002 to 2017
$2.3M
DNA Methylation Profiling of Chronic PainR21NS062271 · NINDS · MAYO CLINIC ROCHESTER · PI BEUTLER, ANDREAS S. · 2009 to 2010
$403k
NIA NIH HHS R37 AG008796NIGMS NIH HHS R25 GM109439NIMH NIH HHS T32 MH020065NINDS NIH HHS R01 NS062771NINDS NIH HHS R21 NS062271
6 · The paper itself

Abstract

Cerebellar-based learning is thought to rely on synaptic plasticity, particularly at synaptic inputs to Purkinje cells. Recently, however, other complementary mechanisms have been identified. Intrinsic plasticity is one such mechanism, and depends in part on the downregulation of calcium-dependent SK-type K

Indexed as

AnimalsBlinkingConditioning, ClassicalLearningMaleMiceMice, Inbred C57BLNeuronal PlasticityPurkinje CellsSmall-Conductance Calcium-Activated Potassium ChannelsSmall-Conductance Calcium-Activated Potassium Channelscerebellumengramlearningmemoryneuronplasticity

Identifiers

PMID32015022
PMCPMC7055141
OpenAlexW3004016331

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.