Evidence map›Paper›PMID 32015007›Full record

ArticleGlobal health, science and practice2020

A Qualitative Assessment of Provider and Client Experiences With 3- and 6-Month Dispensing Intervals of Antiretroviral Therapy in Malawi.

Julie Hubbard, Khumbo Phiri, Corrina Moucheraud, Kaitlyn McBride, Ashley Bardon, Kelvin Balakasi, Eric Lungu, Kathryn Dovel, Gift Kakwesa, Risa M Hoffman

Abstract read
In one paragraph

Article in Global health, science and practice, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  12. Monitoring patients on ART within the CCMDD programme and those attending an urban healthcare facility in KwaZulu-Natal.South African family practice : official journal of the South African Academy of Family Practice/Primary Care · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Julie HubbardUniversity of California Los Angeles, David Geffen School of Medicine, Division of Infectious Diseases, Los Angeles, CA, USA. julieannehubbard@outlook.com.
Khumbo PhiriPartners in Hope Medical Center, Lilongwe, Malawi.
Corrina MoucheraudUniversity of California Los Angeles, Fielding School of Public Health, Department of Health Policy and Management, Los Angeles, CA, USA.
Kaitlyn McBrideUniversity of California Los Angeles, Fielding School of Public Health, Department of Health Policy and Management, Los Angeles, CA, USA.
Ashley BardonUniversity of Washington, School of Public Health, Department of Epidemiology, Seattle, WA, USA.
Kelvin BalakasiPartners in Hope Medical Center, Lilongwe, Malawi.
Eric LunguPartners in Hope Medical Center, Lilongwe, Malawi.
Kathryn DovelUniversity of California Los Angeles, David Geffen School of Medicine, Division of Infectious Diseases, Los Angeles, CA, USA.
Gift KakwesaPartners in Hope Medical Center, Lilongwe, Malawi.
Risa M HoffmanUniversity of California Los Angeles, David Geffen School of Medicine, Division of Infectious Diseases, Los Angeles, CA, USA.

Funding

Scientific and Technical CoreP2CHD041022 · NICHD · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI PATRICK C. HEUVELINE · 2016 to 2026
$6.9M
CALIFORNIA CENTER FOR POPULATION TRAINING PROGRAMT32HD007545 · NICHD · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI HIRAM BELTRAN-SANCHEZ, Megan M Sweeney · 2001 to 2026
$4.1M
Innovative strategies to increase ART Initiation and viral suppression among HIV+ men in MalawiK01TW011484 · FIC · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI DOVEL, KATHRYN L · 2019 to 2023
$717k
FIC NIH HHS K01 TW011484NICHD NIH HHS P2C HD041022NICHD NIH HHS T32 HD007545PEPFAR AID-OAA-A-15-00070
6 · The paper itself

Abstract

introductionMultimonth dispensing (MMD) of antiretroviral therapy (ART) is a differentiated model of care that can help overcome health system challenges and reduce the burden of HIV care on clients. Although 3-month dispensing has been the standard of care, interest has increased in extending refill intervals to 6 months. We explored client and provider experiences with MMD in Malawi as part of a cluster randomized trial evaluating 3- versus 6-month ART dispensing.

methodsSemi-structured in-depth interviews were conducted with 17 ART providers and 62 stable, adult clients with HIV on ART. Clients and providers were evenly divided by arm and were eligible for an interview if they had been participating in the study for 1 year (clients) or 6 months (providers). Questions focused on perceived challenges and benefits of the 3- or 6-month amount of ART dispensing. Interviews were transcribed, and data were coded and analyzed using constant comparison.

resultsBoth clients and providers reported that the larger medication supply had benefits. Clients reported decreased costs due to less frequent travel to the clinic and increased time for income-generating activities. Clients in the 6-month dispensing arm reported a greater sense of personal freedom and normalcy. Providers felt that the 6-month dispensing interval reduced their workload. They also expressed concerned about clients' challenges with ART storage at home, but clients reported no storage problems. Although providers mentioned the potential risk of clients sharing the larger medication supply with family or friends, clients emphasized the value of ART and reported only rare, short-term sharing, mostly with their spouses. Providers mentioned clients' lack of motivation to seek care for illnesses that might occur between refill appointments.

conclusionsThe 6-month ART dispensing arm was particularly beneficial to clients for decreased costs, increased time for income generation, and a greater sense of normalcy. Providers' concerns about storage, sharing, and return visits to the facility did not emerge in client interviews. Further data are needed on the feasibility of implementing a large-scale program with 6-month dispensing.

Indexed as

Attitude of Health PersonnelAttitude to HealthCost of IllnessDelivery of Health CareWorkloadAdultAnti-HIV AgentsDrug StorageFemaleHIV InfectionsHumansMalawiMaleMiddle AgedPharmaceutical ServicesQualitative ResearchAnti-HIV Agents

Identifiers

PMID32015007
PMCPMC7108939

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.