Evidence map›Paper›PMID 32014993›Full record

ArticleThe Journal of biological chemistry2020

Influence of sulfonated and diet-derived human milk oligosaccharides on the infant microbiome and immune markers.

Candice Quin, Sara D Vicaretti, Nina A Mohtarudin, Alexander M Garner, Deanna M Vollman, Deanna L Gibson, Wesley F Zandberg

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 68 citations in OpenAlex.

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  9. Identifying Factors Associated With Breastfeeding Length Among Filipino Migrant Women in South Korea.Journal of human nutrition and dietetics : the official journal of the British Dietetic Association · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Candice QuinDepartment of Biology, I. K. Barber School of Arts and Sciences, University of British Columbia, 1177 Research Road, Kelowna, British Columbia, Canada V1V 1V7.
Sara D VicarettiDepartment of Chemistry, I. K. Barber School of Arts and Sciences, University of British Columbia, 3247 University Way, Kelowna, British Columbia, Canada V1V 1V7.
Nina A MohtarudinDepartment of Biology, I. K. Barber School of Arts and Sciences, University of British Columbia, 1177 Research Road, Kelowna, British Columbia, Canada V1V 1V7.
Alexander M GarnerDepartment of Biology, I. K. Barber School of Arts and Sciences, University of British Columbia, 1177 Research Road, Kelowna, British Columbia, Canada V1V 1V7.
Deanna M VollmanDepartment of Biology, I. K. Barber School of Arts and Sciences, University of British Columbia, 1177 Research Road, Kelowna, British Columbia, Canada V1V 1V7.
Deanna L GibsonDepartment of Biology, I. K. Barber School of Arts and Sciences, University of British Columbia, 1177 Research Road, Kelowna, British Columbia, Canada V1V 1V7 Deanna.Gibson@ubc.ca.
Wesley F ZandbergDepartment of Chemistry, I. K. Barber School of Arts and Sciences, University of British Columbia, 3247 University Way, Kelowna, British Columbia, Canada V1V 1V7 wesley.zandberg@ubc.ca.ORCID 0000-0002-5857-9006
University of British Columbia · CA

Funding

CIHR
6 · The paper itself

Abstract

Human milk oligosaccharides (HMOs) promote the development of the neonatal intestinal, immune, and nervous systems and has recently received considerable attention. Here we investigated how the maternal diet affects HMO biosynthesis and how any diet-induced HMO alterations influence the infant gut microbiome and immunity. Using capillary electrophoresis and MS-based analyses, we extracted and measured HMOs from breast milk samples and then correlated their levels with results from validated 24-h diet recall surveys and breast milk fatty acids. We found that fruit intake and unsaturated fatty acids in breast milk were positively correlated with an increased absolute abundance of numerous HMOs, including 16 sulfonated HMOs we identified here in humans for the first time. The diet-derived monosaccharide 5-

Indexed as

BacteroidesCarbohydrate SequenceDietElectrophoresis, CapillaryFatty Acids, UnsaturatedFecesGastrointestinal MicrobiomeHumansInfantInfant, NewbornInterleukin-10Interleukin-13Mass SpectrometryMilk, HumanNeuraminic AcidsOligosaccharidesFatty Acids, UnsaturatedInterleukin-10Interleukin-13Neuraminic AcidsOligosaccharidesSulfonic Acidscapillary electrophoresiscytokinedietglycobiologymicrobiomeMSoligosaccharideprebioticsialic acid

Identifiers

PMID32014993
PMCPMC7086044
OpenAlexW3005359476

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.