Evidence map›Paper›PMID 32014892›Full record

ArticleInfection and immunity2020

Immediate Interferon Gamma Induction Determines Murine Host Compatibility Differences between Toxoplasma gondii and Neospora caninum.

Rachel S Coombs, Matthew L Blank, Elizabeth D English, Yaw Adomako-Ankomah, Ifeanyi-Chukwu Samuel Urama, Andrew T Martin, Felix Yarovinsky, Jon P Boyle

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Infection and immunity, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.7field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 8 citations in OpenAlex.

  1. TheMicroorganisms · 2026
    Review
  2. Toxoplasma gondii and the Brain: Frenemies? Or Just Outright Foes?Journal of the Pediatric Infectious Diseases Society · 2025
    Review
  3. Archives of Razi Institute · 2025
    Article
  4. Article
  5. Article
  6. Review
  7. A Comparison of Stage Conversion in the Coccidian ApicomplexansFrontiers in cellular and infection microbiology · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Rachel S CoombsDepartment of Biological Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.ORCID 0000-0001-5064-6270
Matthew L BlankDepartment of Biological Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Elizabeth D EnglishDepartment of Biological Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.ORCID 0000-0002-2246-8697
Yaw Adomako-AnkomahDepartment of Biological Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Ifeanyi-Chukwu Samuel UramaDepartment of Biological Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Andrew T MartinCenter for Vaccine Biology and Immunology, Department of Microbiology and Immunology, University of Rochester, Rochester, New York, USA.
Felix YarovinskyCenter for Vaccine Biology and Immunology, Department of Microbiology and Immunology, University of Rochester, Rochester, New York, USA.
Jon P BoyleDepartment of Biological Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania, USA boylej@pitt.edu.
University of Pittsburgh · USUniversity of Rochester Medical Center · US

Funding

VECTOR CORE FACILITYP30CA047904 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI CHRISTOPHER J. BAKKENIST · 1988 to 2026
$158.0M
Mucosal immunity to Toxoplasma gondiiR01AI136538 · NIAID · UNIVERSITY OF ROCHESTER · PI Felix Yarovinsky · 2018 to 2026
$4.0M
Comparative and functional genomics of Toxoplasma and Hammondia hammondiR01AI116855 · NIAID · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BOYLE, JON P · 2015 to 2024
$3.2M
Neutrophil IFN-gamma in host defense and inflammationR01AI121090 · NIAID · UNIVERSITY OF ROCHESTER · PI YAROVINSKY, FELIX · 2016 to 2020
$2.3M
Effector diversification and Toxoplasma virulenceR01AI114655 · NIAID · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BOYLE, JON P · 2015 to 2019
$1.9M
NCI NIH HHS P30 CA047904NIAID NIH HHS R01 AI114655NIAID NIH HHS R01 AI116855NIAID NIH HHS R01 AI121090NIAID NIH HHS R01 AI136538
6 · The paper itself

Abstract

Rodents are critical for the transmission of

Indexed as

AnimalsCoccidiosisImmunologic FactorsInterferon-gammaInterleukin-12MiceMice, KnockoutMyeloid Differentiation Factor 88NeosporaRodent DiseasesSurvival AnalysisTime FactorsToxoplasmaToxoplasmosis, AnimalIFNG protein, mouseImmunologic FactorsInterferon-gammaInterleukin-12Myd88 protein, mouseMyeloid Differentiation Factor 88host-pathogen interactionshost responseIL-12innate immunityinterferon gammaMyD88Neospora caninumprofilinTLR11Toxoplasma gondii

Identifiers

PMID32014892
PMCPMC7093116
OpenAlexW3003672074

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.