ArticleBMJ open2020
Patients' perspectives of tuberculosis treatment challenges and barriers to treatment adherence in Ukraine: a qualitative study.
Article in BMJ open, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
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Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Effectiveness of health education in improving treatment adherence among patients with chronic communicable diseases: A systematic review and meta-analysis.Tropical medicine & international health : TM & IH · 2025Pooled it
- Article
- Psychosocial challenges of drug-resistant tuberculosis: A qualitative study in Deoghar, Eastern India.The Indian journal of medical research · 2026Review
- Drug-resistant TB treatment outcomes and factors associated with discontinuation and LTFU in Germany: No1Lost study protocol.IJTLD open · 2026Article
- Article
- Depression among people living with tuberculosis and tuberculosis/HIV coinfection in Ukraine: a cross-sectional study.Global health action · 2025Article
- Associations of municipality-level income and racial segregation with individual-level tuberculosis treatment outcomes in Brazil: a nationwide cohort study (2010-2019).Journal of epidemiology and community health · 2025Article
- Process Evaluation of Pragmatic Cluster-Randomized Trials of Digital Adherence Technologies for Tuberculosis Treatment Support: A Mixed-Method Study in Five Countries.Tropical medicine and infectious disease · 2025Article
- Integrating narrative and bibliometric approaches to examine factors and impacts of tuberculosis treatment non-compliance.Multidisciplinary respiratory medicine · 2025Article
- Treatment preferences among people at risk of developing tuberculosis: A discrete choice experiment.PLOS global public health · 2024Article
- "It is not easy": Experiences of people living with HIV and tuberculosis on Tuberculosis treatment in Uganda.Journal of clinical tuberculosis and other mycobacterial diseases · 2023Article
- Hepatitis C care cascade among patients with and without tuberculosis: Nationwide observational cohort study in the country of Georgia, 2015-2020.PLoS medicine · 2023Observational
- Rethinking intercurrent events in defining estimands for tuberculosis trials.Clinical trials (London, England) · 2022Article
- Time Trend Analysis of Tuberculosis Treatment While Using Digital Adherence Technologies-An Individual Patient Data Meta-Analysis of Eleven Projects across Ten High Tuberculosis-Burden Countries.Tropical medicine and infectious disease · 2022Article
- The contribution of drug import to the cost of tuberculosis treatment: A cost analysis of longer, shorter, and short drug regimens for Karakalpakstan, Uzbekistan.PLOS global public health · 2022Article
- Appraisal on patient compliance and factors influencing the daily regimen of anti-tubercular drugs in Mangalore city: A cross-sectional study.F1000Research · 2022Article
- Does tuberculosis screening improve individual outcomes? A systematic review.EClinicalMedicine · 2021Article
- TB stigma and its correlates among HIV-positive people who inject drugs in Ukraine.The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease · 2021Article
- Exploring community tuberculosis program in the pastoralist setting of Ethiopia: a qualitative study of community health workers' perspectives in Borena Zone, Oromia Region.BMC health services research · 2021Article
- Development and Psychometric Testing of the Supportive Care Needs Scale for Patients with Tuberculosis (SCN-TB).Patient preference and adherence · 2021Article
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Authors and funding
10 authors.
Funding
Abstract
objectivesTo understand the challenges faced by patients with tuberculosis (TB) and factors that influence TB treatment adherence in Ukraine.
designQualitative study.
settingTB treatment facilities in Kyiv Oblast, Ukraine.
participantsSixty adults who had undergone treatment for drug-sensitive TB between June 2012 and August 2015.
methodsWe conducted semistructured, in-depth, individual interviews among a purposively selected clinical sample of patients previously treated for drug-sensitive TB. Interview content encompassed WHO's framework for barriers to adherence to long-term therapies and included questions about patient preferences and motivators concerning treatment adherence. We examined treatment experience across strata defined by previously identified risk correlates of non-adherence.
resultsAmong 60 participants, 19 (32.8%) were HIV positive, 12 (20.3%) had substance use disorder and 9 (15.0%) had not completed TB treatment. Respondents discussed the psychological distress associated with hospital-based TB care, as well as perceived unsupportive, antagonistic interactions with TB providers as major challenges to treatment adherence. An additional barrier to successful treatment completion included the financial toll of lost income during TB treatment, which was exacerbated by the additional costs of ancillary medications and transportation to ambulatory TB clinics. The high pill burden of TB treatment also undermined adherence. These challenges were endorsed among participants with and without major risk factors for non-adherence.
conclusionsOur findings highlight important barriers to TB treatment adherence in this study population and suggest specific interventions that may be beneficial in mitigating high rates of poor treatment outcomes for TB in Ukraine.
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