Evidence map›Paper›PMID 32014085›Full record

ArticleComparative medicine2020

Effect of Chronic Vitamin D Deficiency on the Development and Severity of DSS-Induced Colon Cancer in

Stacey M Meeker, Audrey Seamons, Piper M Treuting, Jisun Paik, Thea Brabb, Charlie C Hsu, William M Grady, Lillian Maggio-Price

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Comparative medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 2 pooled it
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 2 syntheses or guidelines pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Stacey M MeekerDepartment of Comparative Medicine, University of Washington, Seattle, Washington; Ohio State University, Columbus, Ohio;, Email: meeker.79@osu.edu.
Audrey SeamonsDepartment of Comparative Medicine, University of Washington, Seattle, Washington.
Piper M TreutingDepartment of Comparative Medicine, University of Washington, Seattle, Washington.
Jisun PaikDepartment of Comparative Medicine, University of Washington, Seattle, Washington.
Thea BrabbDepartment of Comparative Medicine, University of Washington, Seattle, Washington.
Charlie C HsuDepartment of Comparative Medicine, University of Washington, Seattle, Washington.
William M GradyOhio State University, Columbus, Ohio.
Lillian Maggio-PriceDepartment of Comparative Medicine, University of Washington, Seattle, Washington.
University of Washington · USThe Ohio State University · US

Funding

UNIVERSITY OF WASHINGTON GI TRAINING GRANTT32DK007742 · NIDDK · UNIVERSITY OF WASHINGTON · PI GRADY, WILLIAM MALLORY · 1996 to 2022
$4.7M
Vitamin D mediated protection in inflammatory bowel diseaseK01OD021420 · OD · UNIVERSITY OF WASHINGTON · PI MEEKER, STACEY MARIE · 2016 to 2019
$592k
Control of Colonic Inflammation and Tumor Growth by TGFBeta and Dietary Vitamin DR21CA149995 · NCI · UNIVERSITY OF WASHINGTON · PI MAGGIO-PRICE, LILLIAN · 2011 to 2012
$373k
NCI NIH HHS R21 CA149995NIDDK NIH HHS T32 DK007742NIH HHS K01 OD021420
6 · The paper itself

Abstract

Both human epidemiologic data and animal studies suggest that low serum vitamin D increases the risk of inflammatory bowel disease (IBD) and consequently IBD-associated colorectal cancer. We tested the hypothesis that vitamin D deficiency increases the risk for colitis-associated colon cancer (CAC) by using an established CAC mouse model, 129-

Indexed as

AnimalsColitisColonColonic NeoplasmsDisease Models, AnimalMiceSignal TransductionVitamin DVitamin D Deficiency25-hydroxyvitamin DVitamin D

Identifiers

PMID32014085
PMCPMC7137544
OpenAlexW3004878786

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.