ArticleBMC veterinary research2020
Effect of Lactobacillus spp. on adhesion, invasion, and translocation of Campylobacter jejuni in chicken and pig small-intestinal epithelial cell lines.
Article in BMC veterinary research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed, 36 citations in OpenAlex.
- Lactococcus cremoris decreases virulence‑associated properties, and modifies the protein profile of foodborne pathogen Campylobacter jejuni in biofilm.Gut pathogens · 2026Article
- Encapsulated probiotics as antimicrobial agents: mechanisms and delivery strategies against multidrug-resistant pathogens.Frontiers in cellular and infection microbiology · 2026Review
- Article
- The Efficacy of a Ferric Sillen Core-Linked Polymer in Suppressing the Pathogenicity ofAnimals : an open access journal from MDPI · 2024Article
- Protective Capacity ofPharmaceuticals (Basel, Switzerland) · 2024Article
- In vitro investigations on interference of selected probiotic candidates with Campylobacter jejuni adhesion and invasion of primary chicken derived cecal and Caco-2 cells.Gut pathogens · 2024Article
- The improvement of immunity and activation of TLR2/NF-κB signaling pathway by Romboutsia ilealis in broilers.Journal of animal science · 2024Article
- The Effect of Maternal Probiotic or Synbiotic Supplementation on Sow and Offspring Gastrointestinal Microbiota, Health, and Performance.Animals : an open access journal from MDPI · 2023Review
- Transcriptomic, 16S ribosomal ribonucleic acid and network pharmacology analyses shed light on the anticoccidial mechanism of green tea polyphenols against Eimeria tenella infection in Wuliangshan black-boned chickens.Parasites & vectors · 2023Article
- In silico prediction and expression analysis of vaccine candidate genes of Campylobacter jejuni.Poultry science · 2023Article
- Application ofLife (Basel, Switzerland) · 2023Article
- Impact of a direct-fed microbial supplementation on intestinal permeability and immune response in broiler chickens during a coccidia challenge.Frontiers in microbiology · 2023Article
- Anti-Foodborne pathogens and disease · 2022Review
- Gastrointestinal Microbiota and Their Manipulation for Improved Growth and Performance in Chickens.Foods (Basel, Switzerland) · 2022Review
- The Role of Nutraceuticals and Phytonutrients in Chickens' Gastrointestinal Diseases.Animals : an open access journal from MDPI · 2022Review
- Effects of α-glycerol monolaurate on intestinal morphology, nutrient digestibility, serum profiles, and gut microbiota in weaned piglets.Journal of animal science · 2022Article
- A buffalo rumen-derived probiotic (SN-6) could effectively increase simmental growth performance by regulating fecal microbiota and metabolism.Frontiers in microbiology · 2022Article
- Enterococcus faecium PNC01 isolated from the intestinal mucosa of chicken as an alternative for antibiotics to reduce feed conversion rate in broiler chickens.Microbial cell factories · 2021Article
- Effects of a dietary direct-fed microbial and Ferulago angulata extract on growth performance, intestinal microflora, and immune function of broiler chickens infected with Campylobacter jejuni.Poultry science · 2021Article
- Lactic Acid Bacteria - A Promising Tool for Controlling ChickenFrontiers in microbiology · 2021Review
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundCampylobacter spp. are a major cause of bacterial food-borne diarrhoeal disease. This mainly arises through contamination of meat products during processing. For infection, Campylobacter spp. must adhere to epithelial cells of the mucus layer, survive conditions of the gastrointestinal tract, and colonise the intestine of the host. Addition of probiotic bacteria might promote competitive adhesion to epithelial cells, consequently reducing Campylobacter jejuni colonisation. Effect of Lactobacillus spp. (PCS20, PCS22, PCS25, LGG, PCK9) on C. jejuni adhesion, invasion and translocation in pig (PSI cl.1) and chicken (B1OXI) small-intestine cell lines, as well as pig enterocytes (CLAB) was investigated.
resultsOverall, in competitive adhesion assays with PSI cl.1 and CLAB cell monolayers, the addition of Lactobacillus spp. reduced C. jejuni adherence to the cell surface, and negatively affected the C. jejuni invasion. Interestingly, Lactobacillus spp. significantly impaired C. jejuni adhesion in three-dimensional functional PSI cl.1 and B1OXI cell models. Also, C. jejuni did not translocate across PSI cl.1 and B1OXI cell monolayers when co-incubated with probiotics. Among selected probiotics, Lactobacillus rhamnosus LGG was the strain that reduced adhesion efficacy of C. jejuni most significantly under co-culture conditions.
conclusionThe addition of Lactobacillus spp. to feed additives in livestock nutrition might be an effective novel strategy that targets Campylobacter adhesion to epithelial cells, and thus prevents colonisation, reduces the transmission, and finally lowers the incidence of human campylobacteriosis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.