Evidence map›Paper›PMID 32013858›Full record

ArticleBMC genomics2020

Comparative analysis of Lactobacillus gasseri from Chinese subjects reveals a new species-level taxa.

Xingya Zhou, Bo Yang, Catherine Stanton, R Paul Ross, Jianxin Zhao, Hao Zhang, Wei Chen

Abstract readComparative Study
In one paragraph

Article in BMC genomics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed.

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  8. Acetate modulates the inhibitory effect ofMicrobial cell (Graz, Austria) · 2023
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  15. Microbiome research reports · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Xingya ZhouState Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi, Jiangsu, China.
Bo YangState Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi, Jiangsu, China. bo.yang@jiangnan.edu.cn.ORCID http://orcid.org/0000-0002-1347-3718
Catherine StantonInternational Joint Research Center for Probiotics & Gut Health, Jiangnan University, Wuxi, Jiangsu, China.
R Paul RossInternational Joint Research Center for Probiotics & Gut Health, Jiangnan University, Wuxi, Jiangsu, China.
Jianxin ZhaoState Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi, Jiangsu, China.
Hao ZhangState Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi, Jiangsu, China. zhanghao61@jiangnan.edu.cn.
Wei ChenState Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi, Jiangsu, China.

Funding

Fundamental Research Funds for the Central Universities JUSRP11733National Firs-Class Discipline Program of Food Science and Technology JUFSTR20180102National Natural Science Foundation of China Nos. 31530056, 31820103010, 31801521
6 · The paper itself

Abstract

backgroundLactobacillus gasseri as a probiotic has history of safe consumption is prevalent in infants and adults gut microbiota to maintain gut homeostasis.

resultsIn this study, to explore the genomic diversity and mine potential probiotic characteristics of L. gasseri, 92 strains of L. gasseri were isolated from Chinese human feces and identified based on 16 s rDNA sequencing, after draft genomes sequencing, further average nucleotide identity (ANI) value and phylogenetic analysis reclassified them as L. paragasseri (n = 79) and L. gasseri (n = 13), respectively. Their pan/core-genomes were determined, revealing that L. paragasseri had an open pan-genome. Comparative analysis was carried out to identify genetic features, and the results indicated that 39 strains of L. paragasseri harboured Type II-A CRISPR-Cas system while 12 strains of L. gasseri contained Type I-E and II-A CRISPR-Cas systems. Bacteriocin operons and the number of carbohydrate-active enzymes were significantly different between the two species.

conclusionsThis is the first time to study pan/core-genome of L. gasseri and L. paragasseri, and compare their genetic diversity, and all the results provided better understating on genetics of the two species.

Indexed as

AdultAsian PeopleBacterial ProteinsBacteriocinsCRISPR-Cas SystemsDNA, BacterialFecesGenome, BacterialGenomicsHumansInfantLactobacillus gasseriPhylogenyProbioticsRNA, Ribosomal, 16SBacterial ProteinsBacteriocinsDNA, BacterialRNA, Ribosomal, 16SANIGenotypeLactobacillus gasseriLactobacillus paragasseriPan/core-genome

Identifiers

PMID32013858
PMCPMC6998098

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.